ID A0A1H3CD87_9PSED Unreviewed; 911 AA.
AC A0A1H3CD87;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216287_3208 {ECO:0000313|EMBL:SDX52083.1};
OS Pseudomonas kuykendallii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1007099 {ECO:0000313|EMBL:SDX52083.1, ECO:0000313|Proteomes:UP000243778};
RN [1] {ECO:0000313|Proteomes:UP000243778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-59562 {ECO:0000313|Proteomes:UP000243778};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNNU01000004; SDX52083.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3CD87; -.
DR STRING; 1007099.SAMN05216287_3208; -.
DR Proteomes; UP000243778; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SDX52083.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000243778};
KW Transferase {ECO:0000313|EMBL:SDX52083.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 395..616
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 768..889
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 819
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 911 AA; 101324 MW; B471BD3F917378FF CRC64;
MPVAPLDQDE LRLSLGPYVG ILEDPEGLLD IEQVRRIEDR LFRPAPGVYP NMGKSRSTWW
LKVDLRNSRP HTLDGFIEVN YPLLDDIQLY LIAPDGTLTR QAGGDTHPFG ERPVPVRNFW
FPTRVPPGDS VLLVRVQTTS TAFVPLFFAT HAASASAQEV AMGFNGAFYG VLFAMFCYNL
FLYLSLREPA YFWYLMYNVN IGLFAASFDG LMFQMLPDWL ELEALGIYAL MYSHCLFALQ
FSRHFLHTRQ HFPSMDRALQ LLMLGTVVCL CSEPLIGMMA WTILASLTVL TVSFFSLLAG
IYVWNAGLRY GSYYMLAWGV LLLTFIQATT GSLGLEVFGI YGATAVKIGV TVELITLSIG
LADRINLLKE EGFLSRQTAE QAVIENKAKS RFLATMSHEI RTPLNGVLGM LQLLKETSLD
RSQRFYVETI ASSGTALMAV INDILDYARI ESGKLTLENI SFDLEELVSD TLSLFTAQAM
EKRLRLHVSL EGGVPQRIKG DPTRLKQVLM NLLGNAIKFT AEGHVALGVT RRTDARGQEQ
LVFSVSDSGI GMRREVLNTL FQSFAQGDSS TTRRYGGSGL GLAISKELVE MMGGRIEAQS
KLGQGTRFTF DIPLQAEPDT DELRHLLEGQ HALLASLDAT ALETVGHLLR RWGIHTEHCQ
SPEHLLERLE SAPSPQLLVL MAPWPGSAEY WLDSLRSSLA PGQRVLLLCP PEQCQRVPAS
QVLKLFALAQ PISVKPLREA LLKVYDRTEE LPPEAAPAPR QALGDAPCVL VAEDNAVNQL
VVQGFLRKRG YRIRLVSNGV AAVEEYRHFP RGVQAILMDC EMPEMDGFEA TRRIRQLERE
QDLPPVPIIA LTAHILEEHR QQGAAVGMDD FLGKPLDSLL LYATLERYLP RPSPAAAPVV
EGTDDHSRPA R
//
