ID A0A1H3DMV5_9PSEU Unreviewed; 861 AA.
AC A0A1H3DMV5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216215_1013173 {ECO:0000313|EMBL:SDX67843.1};
OS Saccharopolyspora shandongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=418495 {ECO:0000313|EMBL:SDX67843.1, ECO:0000313|Proteomes:UP000199529};
RN [1] {ECO:0000313|EMBL:SDX67843.1, ECO:0000313|Proteomes:UP000199529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDX67843.1,
RC ECO:0000313|Proteomes:UP000199529};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNOK01000013; SDX67843.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3DMV5; -.
DR STRING; 418495.SAMN05216215_1013173; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000199529; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion channel {ECO:0000313|EMBL:SDX67843.1};
KW Ion transport {ECO:0000313|EMBL:SDX67843.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDX67843.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:SDX67843.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 629..841
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 841..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 861 AA; 92648 MW; B261A671673DEA5D CRC64;
MPRGRLRVYL GAAPGVGKTY AMLCEGHRRQ DRGTDVVVGY VETYDRPRTA ELLDGLEVLP
RRTLGYRGAA FTELDVDAVL ARRPEVALID ELAHTNVPGS GRTKRWQDIE EVLDAGIDVI
STVNIQHLES LNDVVEHITG IPQRETVPDE VVRRAEQVEL VDMTAEALRR RMAHGNVYPP
EKIDAALSNY FRVGNLTALR ELALLWLADK VDEQLDSYRA AHDITGTWEA RERVVVALTG
GAEGETLIRR AARIAERARG ADLLAVHVVR GDGLSDASPA HLARQRALIE DLGGTYHQVV
GEDIPSALLD FARGVNATQL VLGASRRGRL AQLFSRGVGV TTTARSGPID VHMVTHERVG
HRQWLPTFAP GVGWRRRIAG FALAALGIPL LTALLELARN DLSLPSEILL FLVLVVGIAL
VGGCWPAISA ALAAFLVLNY YFTPPLYVWT IADPDNLLAL IVFAVVAIAV SAVVDLAARR
AREAARARAE AAVLSNLAGS VLRGEHPLSA LLSRLRETFA QDSATLLERR PESGRTPEEQ
HDPRAWHVVD AAGAPPCPSP DAGDTHIAVG EDLALALRGP TLPAADRRVL EAFATQAAVA
LHQHRLAEQA EQSRQLTAAN EMRTALLAAV SHDLRTPLAS ASAAVESLLS DDVAWSEEDE
AELLDAAYQS LVRLDRLVAN LLDMSRLQSG TLGIATRQLA VADAVPQALD GLDANGRVRI
QIPEALPDVL ADPGLLERVL ANLIGNALHY NPPGRSVLVT ASALADHVEV RIIDRGPGVR
PEDQEKIFLP FQRLGDRDKN TGVGLGLALA RGLTEAMHGT LTPDETPGGG LTMVLTLPTA
EPPAIPAQSS AERPTPRGSI R
//
