ID A0A1H3E8D1_9EURY Unreviewed; 934 AA.
AC A0A1H3E8D1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cu2+-exporting ATPase {ECO:0000313|EMBL:SDX75003.1};
GN ORFNames=SAMN05216564_101329 {ECO:0000313|EMBL:SDX75003.1};
OS Halopenitus persicus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halopenitus.
OX NCBI_TaxID=1048396 {ECO:0000313|EMBL:SDX75003.1, ECO:0000313|Proteomes:UP000199079};
RN [1] {ECO:0000313|EMBL:SDX75003.1, ECO:0000313|Proteomes:UP000199079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC30,IBRC 10041,KCTC 4046 {ECO:0000313|Proteomes:UP000199079};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNPC01000001; SDX75003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3E8D1; -.
DR OrthoDB; 8588at2157; -.
DR Proteomes; UP000199079; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01229; COF_2; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..150
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 156..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 934 AA; 94939 MW; C5988491F1F1B123 CRC64;
MSDCRLCGLP TPDQPVTASD VDGAFCCRGC LEVARRLDDL DDVGGTAGGV GGTADGVGSG
AAALEAASDG VVSDSDANAA PDAPEAYLAV EGMHCTTCEA FLRLRGDDVA GVHAVQANYG
TETARVVYDP DEIDREALPE ALSGYGYALR FMEGERTTDG TGKRSNGDDA KPARREGDPG
STSGRSTDPT LERLAIGGFL AMLVMPWYVL SLYPSYLGIE TNVLAIDTTT PVGRYLPLVF
IALVTTILVA TTGAPLLRGA YVSLRARRPN MDLLVTVAAL SAYAYSTLAL ATGSTHLYYD
VTVAVVMVVS LGRYYEGRVR SRATDLLETV TAARVESATR ITDAGRETVP IGALEPGDRI
RVAPGERVPV DGTVIEGVAD VDQSVITGES LPVRAEPGEE VVGGARVLGD VGHGGRDAGC
ESGDGNDDGA AGGAIAVRVG EDAESTADRL AAALWEVQTT TPGIQRFVDA LATVFVPVVL
TLGLAVAAWQ LVAGETVAAA MLAGLTVLVV SCPCAMGLAT PLAVSGGLRD AIARGVVVTD
GSVFESAREA ETVVFDKTGT LTAGEMRVGA VHGDDRTLAR AAAVERRADH PVADAIHEAA
AARADGGGKS GGVVETTETG GAAASAASGT DGPTVESFTH HPGMGVSGTL VDAARDDRVI
PSETAGTDAG GERVVVGTPD LVERECGPLP AALAERVDAA TDDGALPIAV GWGGAARGVI
VVTDRDRAGW TAALEAFADR EVVVLTGDDG PRADRFRGHP AVDEVFAGVP PDGKLEAVRG
FVADGTTVMV GDGTNDAPAL AAADLGIALG DGTARAVEAA DVVITGDDLR TVETVFELAA
GTRRRIRENV AWALCYNAVA IPLAVSGALN PFFAALAMAA SSAIVVTNST RPVLDDDPAS
EASEASEAPD SASGTSDSAS GTSDPASEAS GPAF
//
