ID A0A1H3EDK5_9PSEU Unreviewed; 371 AA.
AC A0A1H3EDK5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Addiction module antidote protein, HigA family {ECO:0000313|EMBL:SDX76822.1};
GN ORFNames=SAMN05421504_103770 {ECO:0000313|EMBL:SDX76822.1};
OS Amycolatopsis xylanica.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=589385 {ECO:0000313|EMBL:SDX76822.1, ECO:0000313|Proteomes:UP000199515};
RN [1] {ECO:0000313|EMBL:SDX76822.1, ECO:0000313|Proteomes:UP000199515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPCC 202699 {ECO:0000313|EMBL:SDX76822.1,
RC ECO:0000313|Proteomes:UP000199515};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
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DR EMBL; FNON01000003; SDX76822.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3EDK5; -.
DR OrthoDB; 9794834at2; -.
DR Proteomes; UP000199515; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.10.2910; -; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR43236; ANTITOXIN HIGA1; 1.
DR PANTHER; PTHR43236:SF1; BLL7220 PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199515}.
FT DOMAIN 22..76
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 42311 MW; DA347F28053A595D CRC64;
MTLGAESLEY SPHTSAPPGE TLKETLEALG ITQVDLARRT GFSTKHVNQI IQGSAVLTPE
TAEVLERVTG VPAALWNTLE AAWRTQAVRE EENKKLRIHL DWLDKFPLAE LVTRKILPDR
SKSVENLRLL LNFFGVANPE VAEELWAGYR IAFRRSGNIE PNDYSVSVWL RQSVRAARKI
ECQPYRRHEL IRLLPELRAL CRRNPETWLT ELPLLCARAG VAVVFLPALK GTHISGATRW
LTTEKVLVAL TDRHKKDDRF WFSFFHEIAH VLLHGKRLTF LDDDPMKYDE DPAEDEANRF
AAEMLIPSKY SYDYERLRIR PKPFVKIEEF AAMVGISPGV VVGRLQHDGA LPWSEGNGLK
QGFKLTLDEL R
//
