ID   A0A1H3FK52_9ACTN        Unreviewed;       333 AA.
AC   A0A1H3FK52;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=RNA polymerase sigma factor, sigma-70 family {ECO:0000313|EMBL:SDX91376.1};
GN   ORFNames=SAMN05444365_10149 {ECO:0000313|EMBL:SDX91376.1};
OS   Micromonospora pattaloongensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=405436 {ECO:0000313|EMBL:SDX91376.1, ECO:0000313|Proteomes:UP000242415};
RN   [1] {ECO:0000313|Proteomes:UP000242415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45245 {ECO:0000313|Proteomes:UP000242415};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNPH01000001; SDX91376.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3FK52; -.
DR   STRING; 405436.SAMN05444365_10149; -.
DR   OrthoDB; 9809557at2; -.
DR   Proteomes; UP000242415; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR   PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242415};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          295..321
FT                   /note="RNA polymerase sigma-70"
FT                   /evidence="ECO:0000259|PROSITE:PS00716"
SQ   SEQUENCE   333 AA;  37259 MW;  1171B470DA660B2C CRC64;
     MNVGTAGKRV RRVNEGTVGN VEKNVVMRTD EVAEERDLVG VYLHEISRTP LLDAAAEVDL
     SKAIEAGLYA EHLLDEGTLP KGVSREELER LVAEGVRGKD LFIRANLRLV VSIARRYVRS
     GMPMLDLIQE GNTGLVRAVE KFDYERGYKF STYATWWIRQ AISRAIAQQE RTVRLPVHLV
     EDVNRMRNVA RQLTRELGSD PEPEQIAAAL GVPVERVHEL VRWSQDTVSL DTPVGDDGDT
     NLGDLVADSD APSPEEIVLT ALERQRIEGL LNHLDDRSAG IMRARYGLED GREHSLTEVA
     SRFSLSRERI RQLEIQALGR LRELARAEGL QAA
//