ID   A0A1H3G7D6_9ACTN        Unreviewed;       185 AA.
AC   A0A1H3G7D6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SDX98558.1};
GN   ORFNames=SAMN05660209_01745 {ECO:0000313|EMBL:SDX98558.1};
OS   Geodermatophilus africanus.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=1137993 {ECO:0000313|EMBL:SDX98558.1, ECO:0000313|Proteomes:UP000198921};
RN   [1] {ECO:0000313|EMBL:SDX98558.1, ECO:0000313|Proteomes:UP000198921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45422 {ECO:0000313|EMBL:SDX98558.1,
RC   ECO:0000313|Proteomes:UP000198921};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNOT01000004; SDX98558.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3G7D6; -.
DR   STRING; 1137993.SAMN05660209_01745; -.
DR   OrthoDB; 6929199at2; -.
DR   Proteomes; UP000198921; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   InterPro; IPR041583; TetR_C_31.
DR   PANTHER; PTHR47506:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR LMRA; 1.
DR   PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF17940; TetR_C_31; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          14..74
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        37..56
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   185 AA;  20197 MW;  01CB1BC0E7DF5B26 CRC64;
     MTSAPARRPR RHDPGRRDRL LGTTLDVIAE HGVTATTHRA IARAADVPLG SLTYHFASLT
     ELLAAAFTRH VDTVAERFDE RMRAAPDRAA ALEALVGHLT DDLLGSSRDL VLAVELYVAA
     ARDPALRAVT QDWMSRSRRS LERHLDPVTA REVDALVEGL VLHSALSTDP MDADQIRSAL
     LRLAG
//