ID   A0A1H3GEW2_9PSED        Unreviewed;       664 AA.
AC   A0A1H3GEW2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SDY00839.1};
GN   ORFNames=SAMN05216287_4313 {ECO:0000313|EMBL:SDY00839.1};
OS   Pseudomonas kuykendallii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1007099 {ECO:0000313|EMBL:SDY00839.1, ECO:0000313|Proteomes:UP000243778};
RN   [1] {ECO:0000313|Proteomes:UP000243778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-59562 {ECO:0000313|Proteomes:UP000243778};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FNNU01000009; SDY00839.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3GEW2; -.
DR   STRING; 1007099.SAMN05216287_4313; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000243778; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243778};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          299..607
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   664 AA;  74843 MW;  93A41AC9B22A9042 CRC64;
     MSVRNFLVKM PRRYKRLVQV GADVLLVWLA LWAAFVVRLG LDDRVDPLGE HFWLFAIAPM
     VSIPIFVRLG MYRAVMRYLG NDALITIFKA VTLSALVFAL VFYWYRVPLN VVPRSIVFNY
     WWISLLLIGG LRLTMRQYFL GDWYIARQQL PFLKHDDRLT RVAIYGAGAA GNQLVSALRM
     GQSMRPVAFI DDDDSIATRI ISGLKVYKPK HIEQMINDTG AQEILLAIPS ASRMRRREVL
     VLLEKHPLHV RSVPGFMDLA SGRVKVDDIQ EVDIADLLGR EVVPPRQALF ERCIRRQVVM
     VTGAGGSIGS ELCRQILLNA PTTLLLFEHS EFNLYSIHSE LEERIRRESL PLRLVPILGS
     VRDRERLKDV MRTWQVNTVY HAAAYKHVPM VEHNIAEGVL NNVMGSLYTA QAALKAGVEN
     FVLISTDKAV RPTNVMGSSK RLAEMVLQAL SRESAPLLFQ AEPSVHHVNK TRFTMVRFGN
     VLGSSGSVIP RFYEQIRKGG PVTVTHPNIT RYFMTIPEAA QLVIQAGSMG QGGDVFVLDM
     GWPVKIVDLA EKMIRLAGMS VRSESNPNGD IAIEFTGLRP GEKLYEELLI GAEGVTPTDH
     PMIMRANEEW LPWEAFKGVL SNLLAAVDAD DYDRVRQILR ETVSGYAPEG EIVDWIHQKR
     KSEP
//