ID A0A1H3GG60_9ACTN Unreviewed; 426 AA.
AC A0A1H3GG60;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:SDY02342.1};
GN ORFNames=SAMN05444365_101404 {ECO:0000313|EMBL:SDY02342.1};
OS Micromonospora pattaloongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=405436 {ECO:0000313|EMBL:SDY02342.1, ECO:0000313|Proteomes:UP000242415};
RN [1] {ECO:0000313|Proteomes:UP000242415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45245 {ECO:0000313|Proteomes:UP000242415};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
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DR EMBL; FNPH01000001; SDY02342.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3GG60; -.
DR STRING; 405436.SAMN05444365_101404; -.
DR OrthoDB; 9763887at2; -.
DR Proteomes; UP000242415; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000242415};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 337..411
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 426 AA; 43824 MW; 07619C8B5C6625E8 CRC64;
MSAFTAVDVI RVKRDGGVLS DAQIDWVVEA YTRGEVADEQ MSALAMAILL RGMTPGEIAR
WTAAMIASGE RLDLSGVSRP TVDKHSTGGV GDKITLPLTP LVAACGAAVP QLSGRGLGHT
GGTLDKLESI PGWRAVLSND EFTAQLGDVG AVICAAGAGL APADRKLYAL RDVTGTVEAI
PLIASSIMSK KIAEGTGALV LDVKVGSGAF MKSLPDAREL ARTMVDLGGA HGVRTVALLT
DMSTPLGYAI GNAIEVDETL QVLDGAGPAD VVELTLALAR EMLTAAGLPD VDPAEALRDG
RAMDSWRAMI RAQGGDPDAP LPIAAETETV RAERDGVVAA VDAYTMGLTA WRLGAGRARK
EDPVSAAAGV VLHKKPGDPV RVGDPLYELR ADSAARIADG LAAAADAVVV ADRAPAPTPL
VIERIA
//
