ID A0A1H3GSK3_9ACTN Unreviewed; 488 AA.
AC A0A1H3GSK3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=NCS1 nucleoside transporter family {ECO:0000313|EMBL:SDY05299.1};
GN ORFNames=SAMN05661080_02155 {ECO:0000313|EMBL:SDY05299.1};
OS Modestobacter sp. DSM 44400.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Modestobacter.
OX NCBI_TaxID=1550230 {ECO:0000313|EMBL:SDY05299.1, ECO:0000313|Proteomes:UP000199500};
RN [1] {ECO:0000313|EMBL:SDY05299.1, ECO:0000313|Proteomes:UP000199500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44400 {ECO:0000313|EMBL:SDY05299.1,
RC ECO:0000313|Proteomes:UP000199500};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; FNOZ01000013; SDY05299.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3GSK3; -.
DR STRING; 1550230.SAMN05661080_02155; -.
DR OrthoDB; 9809167at2; -.
DR Proteomes; UP000199500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11484; SLC-NCS1sbd_CobB-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000199500};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 37..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 488 AA; 52413 MW; D8E2F19B2EDE96A8 CRC64;
MANARSDTPK VGGVEVRSID YVPLDERHGK LSDLGPLWFM SNAQIATLAV GLISITSGGN
LIWSLIAIIS GALIGTFFMA FHSAQGPQLG LPQMIQSRPQ FGYIGALLVW LFAYLQYAGF
NIFNTVLGAQ ALSTTIHGSP KLWIVIVTAV AFVIALVGYD LIHRFERYLA YGFLLIFGIF
TIGALVTLDF PAGAFSLGGF SWTPFLAQFG VVAGYQISWA IYVSDYSRYL PPDVTVRKTF
LWTYWGSALG AIWLMCLGTV LAAAVSSGEA FDTITAINDA GDRVFTGFGA IVLIFSTLGL
ISVTALNMYG GSLTLISAID SFRKVRPTLA VRIVTIAVTA GLSLIGALGA SEDFLGNFES
FLLLVLYLFI PWTAVNLVDY FIVRRGHYAI AEIFNPRGMY GRWGWRGIGS YLVGFAVMVP
FFSTGEFTGF IAQALGGADL SLFVGLPVAG VLYYVLGKSI DVAAETRVAE AEAAELEAAA
GRHEALGS
//
