ID A0A1H3GUG4_9PSEU Unreviewed; 380 AA.
AC A0A1H3GUG4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:SDY06901.1};
GN ORFNames=SAMN05216215_101995 {ECO:0000313|EMBL:SDY06901.1};
OS Saccharopolyspora shandongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=418495 {ECO:0000313|EMBL:SDY06901.1, ECO:0000313|Proteomes:UP000199529};
RN [1] {ECO:0000313|EMBL:SDY06901.1, ECO:0000313|Proteomes:UP000199529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDY06901.1,
RC ECO:0000313|Proteomes:UP000199529};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNOK01000019; SDY06901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3GUG4; -.
DR STRING; 418495.SAMN05216215_101995; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000199529; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091}.
FT DOMAIN 271..366
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 271..366
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 380 AA; 39804 MW; C40FAB05CBA52D62 CRC64;
MTDELAGYTV AVTAARRAEE LGSLLERRGA RVLHGPALRI LPLADDAELR RASRDCVADP
PDVVVATTGI GFRGWIEAAD GWGIGTELLD ALRPAQLLAR GPKARGAVRA AGLPDPWSPA
SESSAELLEH LLDQPLDGVR VVVQLHGQPL PDFVEALSCA GAEVIEVPVY RWTAPADITA
LDNLLAAVCA REVDAVTFTS APAAASLLSL AAERRCQDEL LAALRGPVLV ACVGPVTHAP
LADHGVPAVI PQRFRIGALV RSLCVALPGR APTLPVGGRQ LQVRGHAAVV DGVVKPLSPQ
GKTLLRALAE RPGRVVSRRS LAEALNGAGN PADEHAVEQA VARLRAALGA PELVQTVIKR
GYRLPLEPMG NASRCADPQP
//
