ID A0A1H3H1K7_9ACTN Unreviewed; 715 AA.
AC A0A1H3H1K7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=ATP-dependent DNA helicase DinG {ECO:0000313|EMBL:SDY08529.1};
GN ORFNames=SAMN05444365_101615 {ECO:0000313|EMBL:SDY08529.1};
OS Micromonospora pattaloongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=405436 {ECO:0000313|EMBL:SDY08529.1, ECO:0000313|Proteomes:UP000242415};
RN [1] {ECO:0000313|Proteomes:UP000242415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45245 {ECO:0000313|Proteomes:UP000242415};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; FNPH01000001; SDY08529.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3H1K7; -.
DR STRING; 405436.SAMN05444365_101615; -.
DR OrthoDB; 9805194at2; -.
DR Proteomes; UP000242415; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:SDY08529.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000242415}.
FT DOMAIN 29..332
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 75065 MW; AC9170981AF0E64C CRC64;
MTATPATDTT PSPRRRRSAR ASAEELLAAA VGAVPGGAAR PGQQQMAAAI EHAVSSREHL
LVQAGTGTGK SLAYLAPALT VDGPVVVSTA TLALQSQLVD HDLPRLAEAV EPVLGRRPTF
AVLKGRHHYL CLARLDNSNE DEPEDTLFDA PAPAGTKWLG EAGRLGKQIQ RLRDWALETD
TGDRDELDPG VDDQAWRLVS MPARECVGAA RCPYGDECFA EASRARAREA DVVVTNHSLL
AVDMLAGRHI VPPHKLLIVD EAHELADRVS SAAQAELVPE LIDRAARRAR PLLPADSAEL
LVEAGDALAV GLAETPGGRL TAGLPPALRE ACTLLDAATR AGLEAIGDIK ADDPDPVRKQ
QAKAVLDELS TTTQRLLEEA DHDVAWVEKP EGAGAGRRAL VVAPLSVAGT LATHLYDERT
VVATSATLAL GGRFDTVARA LGLGPAPAPD PSPAAAALAT AAGGRRVPAA SDRDDRRAAT
RAERDGHGAT EGPGWRSLDV GSPFDYPRQG ILYVAAHLPR PAASGLPDAA GEELLKLVGT
LGGRTLGLFS SRRAAQQAAE LLRAKTDLPV LLQGEESLPL LVRRFREDRS SCLFGVMSLW
QGVDVPGDAC QLVVIDRLPF PRPDEPLAAA RAAAVDAGGG SGFAAVSVPI AAVRLAQGVG
RLIRATGDKG VVAVLDSRLE TARGYGAFLR RSLPPFWYTT RPDVVHGALQ RLAAS
//
