ID A0A1H3HPX1_9EURY Unreviewed; 492 AA.
AC A0A1H3HPX1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216564_103383 {ECO:0000313|EMBL:SDY17561.1};
OS Halopenitus persicus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halopenitus.
OX NCBI_TaxID=1048396 {ECO:0000313|EMBL:SDY17561.1, ECO:0000313|Proteomes:UP000199079};
RN [1] {ECO:0000313|EMBL:SDY17561.1, ECO:0000313|Proteomes:UP000199079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC30,IBRC 10041,KCTC 4046 {ECO:0000313|Proteomes:UP000199079};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNPC01000003; SDY17561.1; -; Genomic_DNA.
DR RefSeq; WP_021074115.1; NZ_FNPC01000003.1.
DR AlphaFoldDB; A0A1H3HPX1; -.
DR GeneID; 43837753; -.
DR OrthoDB; 8127at2157; -.
DR Proteomes; UP000199079; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 13..70
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 84..138
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 139..213
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 282..486
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 252..282
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 492 AA; 54799 MW; F11B99CA31E16CE4 CRC64;
MDATGEERES PRTVRSFREA VESAGHSIYW TDTTGTIEYV NPAFEEQTGY TAAEAVGNNA
NILQSGVHDD RFYERLWDTI LAGETWEGEI INQRKDGERY AVKQTISPVT DETGEIVRFV
AINEDVTDLR ESQEQLKRQR DRLADLFDAV PVPLVLVDLE NGDPVVKQVN RRFTETFGYA
GTELGGSSLD AFIADAADAD RVREINDRLQ RGDRVRREVT RTTADGDRRT FLFTGSPLGE
ATDEVLATYI DVTDRKRATE KLERKTQELE RKTETLEEFA SVVSHDLRNP LNVAMGHLDI
LAAEHDDLDV EPIRRAHARM QELIENVLML AKQGRRVDEV RPVPVADCAR ESWDTVETTN
ARLRIEGSRT VQADRNRLRQ LFGNLFRNAV EHGATTSRER PSGTDVEHGD ADVTITVGAT
DDGFYVEDDG PGIPEEERGD VFQAGHTTAD DGTGLGLSIV QEIVEAHGWT IAVTEGTDGG
ARFEITDVNP DA
//
