ID A0A1H3HUD9_9ACTN Unreviewed; 848 AA.
AC A0A1H3HUD9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SDY18364.1};
GN ORFNames=SAMN05444365_101969 {ECO:0000313|EMBL:SDY18364.1};
OS Micromonospora pattaloongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=405436 {ECO:0000313|EMBL:SDY18364.1, ECO:0000313|Proteomes:UP000242415};
RN [1] {ECO:0000313|Proteomes:UP000242415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45245 {ECO:0000313|Proteomes:UP000242415};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNPH01000001; SDY18364.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3HUD9; -.
DR STRING; 405436.SAMN05444365_101969; -.
DR OrthoDB; 3218066at2; -.
DR Proteomes; UP000242415; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242415};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 415..547
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 555..808
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 848 AA; 90360 MW; 64323DC8A028A83B CRC64;
MRHDGSPTST DDQTEERLRL LVGLVVVTAT ICLAVAVAHL TAPPRSLLYP IALAGLVAVT
NALQAKIRVR AQIKAFSSTS AAILVAIALL PPPWVVLCTA AGVALANGLT RNQPIKLAFN
VGKDTTAAAL ASLAAHRAGL LPTLEETGGV AWGPQLVGLL AAAALYTVVD ELLGTRVMAL
ATGRSWRKVA FQDSDSRITF RLANLVIAVA TVAILSYGPG LLLAMPPVVV ALHLSHVGRL
RAQQERRAWQ RLAQTTDELN VVDLDAVLRT AVTRAAQLFS ADQVDVEVHL GPQPRMVRGT
ADAIAYDGPP AEPPGTADAV IRTPLEDHAG GGDVGALRLR FRQPVTLSER EEYTLRTFAS
ALCTAIRNAS AYAELARAAR AHAHAASHDP LTGLANRREL LERGTELLAR RHADGVAALL
LIDLNHFKEI NDTLGHPAGD RVLTEVAHRL REAARPAEVV ARLGGDEFAV LFSGLPAPAM
AAHRAEGLLT ALREPMELEG MRINVEASGG IAVAPGTGGM PELLRRADVA MYQAKRSGQR
IATYARDRDT ADVARLALGG DLPRAVAEHE FTVTFQPIVD LGTGEVLGAE ALARWHHPDR
GSIDPLRFLE TVERSGLLPA FADAVLDQSL AAACAWRDAG FDLPVAVNVS PRSLLDPRFP
SSVVARLQAH DLPPDRLFLE LTETLTISQL EVVDRVLGQL RDAGIRLALD DFGTGYSSLS
VLSRIPVHEL KIDRAFVMAM ENSPEAAAVV RSTVELGRSL ELVVVAEGVE SEPQRRALWE
LGCTAGQGHL FARPMPAPRL LSALRRGSGG RSGSLAPPLH DDGAVIRLTP GRRASGRGRP
DRLPHLPA
//
