ID A0A1H3ISJ2_9CLOT Unreviewed; 712 AA.
AC A0A1H3ISJ2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=SAMN05192546_101271 {ECO:0000313|EMBL:SDY30651.1};
OS Tindallia californiensis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Tindallia.
OX NCBI_TaxID=159292 {ECO:0000313|EMBL:SDY30651.1, ECO:0000313|Proteomes:UP000199230};
RN [1] {ECO:0000313|EMBL:SDY30651.1, ECO:0000313|Proteomes:UP000199230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APO {ECO:0000313|EMBL:SDY30651.1,
RC ECO:0000313|Proteomes:UP000199230};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNPV01000001; SDY30651.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3ISJ2; -.
DR STRING; 159292.SAMN05192546_101271; -.
DR Proteomes; UP000199230; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199230};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 491..649
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 712 AA; 80367 MW; 72F6290A0689C8A0 CRC64;
MGVFEKLSQR RARMQKKRIL EKKKLSAHDE KKILSRKLTW HYVLLGMLFF VTTFYLLLIS
LQPVQYQLRA GQIAPENITS PRMIIDTHTT ENLRREAAEE ITSVYRTDSA VFNEVKNDIE
KFFEKLYQVK QEEEALREQL NQMEDNHLGI TDVHLQAFLQ APEERLNSVE NYLYEIAAQG
MNSGIKVAEL QEEKSEIRDF FNSLTELDEP LKESAIAVIN ATIRPNQFMD VESTEQLREE
AREAITPVVI RRGDILAEQG ERISVDTFVI MKELGLIESE FRPDARLYSG ISSVILLIMA
IMTGYIWLFH PEYFYKTKRI LLLVIIMLLV LISAKPIGVL TIYLIPIATG AMLLTLLLEA
RLALIANAVL SILIAIMAGN DLMILVMGLT GGTVAVLSMI NTKQRGKIFF SGLMVGISNV
IIITSFGLIG NHQTLHVLQD AGMGLFNGIL CAILAIGTLP FWEYSFSILT SVKLIELSNP
SHPLLKQLLM EAPGTYHHSI VVGNLAEAAV NEIGGDGLLV RVGAFYHDIG KVKRPYFFKE
NQFTSENPHD KLAPSLSALI ITGHVKDGIE IGEKNKLPNE ILAFIKEHHG TTLAAYFYHK
AQSECEDPKT IDEMMYRYPG PIPQTRETAI LMLADSAEAA VRSLESPNRD KIEQVIKKII
QSKLEDGQLE DSQLTLTELK DIRQVFAKML AGIMHERIKY PEMDIKELKG RK
//
