ID   A0A1H3ISU5_9BACI        Unreviewed;       344 AA.
AC   A0A1H3ISU5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:SDY30863.1};
GN   ORFNames=SAMN05421736_101920 {ECO:0000313|EMBL:SDY30863.1};
OS   Evansella caseinilytica.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Evansella.
OX   NCBI_TaxID=1503961 {ECO:0000313|EMBL:SDY30863.1, ECO:0000313|Proteomes:UP000198935};
RN   [1] {ECO:0000313|Proteomes:UP000198935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SP {ECO:0000313|Proteomes:UP000198935};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNPI01000001; SDY30863.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3ISU5; -.
DR   STRING; 1503961.SAMN05421736_101920; -.
DR   Proteomes; UP000198935; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   CDD; cd01544; PBP1_GalR; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR30146:SF151; HTH-TYPE TRANSCRIPTIONAL REPRESSOR MELR; 1.
DR   PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198935};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          2..50
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50932"
SQ   SEQUENCE   344 AA;  38317 MW;  F2EA1E9737D12DF0 CRC64;
     MATIKDVARE ANVSISTVSR VLNNDDTIAV MDETRQRIVD IAEQMNYSTN KKNTAPKKKG
     PPAAAMYQIG VMMWGTKEDE RNDPYFLSMR QGIEKRCEEL GMTISKLIRL QTSAKHSLGE
     LDGVIVIGKI APEDIETLYP DHGKLVFLND SPDPVKYDAV VSDLESAAEK AVNHLLEMGH
     ENIGFIGSEE YIQRLFQPRK PVEEARTATY ERMMRKHGWY DAENVYIGDW SSASAYKLMK
     EALTKGALPS AFFIASDPMA VGAVRALNEA GKRVPEDVAV VSIDDIELAS FINPPLTTVK
     IYAEQMGKSA VNLLLERING RDVPVKTVVP IKLIIRESCG WKLR
//