ID   A0A1H3ITY1_9RHOB        Unreviewed;       350 AA.
AC   A0A1H3ITY1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:SDY31027.1};
GN   ORFNames=SAMN05444340_105262 {ECO:0000313|EMBL:SDY31027.1};
OS   Citreimonas salinaria.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Citreimonas.
OX   NCBI_TaxID=321339 {ECO:0000313|EMBL:SDY31027.1, ECO:0000313|Proteomes:UP000199286};
RN   [1] {ECO:0000313|EMBL:SDY31027.1, ECO:0000313|Proteomes:UP000199286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 26880 {ECO:0000313|EMBL:SDY31027.1,
RC   ECO:0000313|Proteomes:UP000199286};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNPF01000005; SDY31027.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3ITY1; -.
DR   STRING; 321339.SAMN05444340_105262; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000199286; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR012824; CobW.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR02475; CobW; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199286}.
FT   DOMAIN          253..347
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   350 AA;  37442 MW;  09C5D38246053604 CRC64;
     MTDLSKLPVT VITGFLGSGK TTLIRHLMQN PGGRRLAVVV NEFGDVGVDG EILKSCAIPD
     CPAENIVELA NGCICCTVAD DFIPTIQALM ALDPRPDHIL IETSGLALPK PLLKAFDWPD
     IRSKITVDGV IALADAEAVA AGRFAPDTAR VQAQREADES IDHETPLSEV FEDQISCADI
     VLLTKPDLAG PDGVAKAKAV IAAEAPRPLP VIEVAEGVVD PRVILGLEAA AEDDIDARPS
     HHDGADDHDH DDFESIVVDI PELSDPRDLV VAIERLANEH NILRVKGYAA VAGKPMRLLV
     QAVGARVRHQ FDRPWRADEG RAGRLVVIAE HDDIQPEAIR AALGALQPAQ
//