ID A0A1H3JE67_9PROT Unreviewed; 332 AA.
AC A0A1H3JE67;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=DNA (Cytosine-5)-methyltransferase 1 {ECO:0000313|EMBL:SDY38202.1};
GN ORFNames=SAMN05421754_100834 {ECO:0000313|EMBL:SDY38202.1};
OS Nitrosomonas sp. Nm58.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=200126 {ECO:0000313|EMBL:SDY38202.1, ECO:0000313|Proteomes:UP000199646};
RN [1] {ECO:0000313|Proteomes:UP000199646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm58 {ECO:0000313|Proteomes:UP000199646};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-
CC methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:11370,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:85452, ChEBI:CHEBI:85454; EC=2.1.1.37;
CC Evidence={ECO:0000256|ARBA:ARBA00000743};
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DR EMBL; FNPQ01000008; SDY38202.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3JE67; -.
DR STRING; 200126.SAMN05421754_100834; -.
DR Proteomes; UP000199646; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF00145; DNA_methylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SDY38202.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199646};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDY38202.1}.
FT REGION 228..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 37000 MW; F7E6CF4B83267A48 CRC64;
MKAYYNEFDR DAAAWLRQLI NGGLIADGEV DERSITEVEA NDLVGFDRCH FFAGVGTWDY
CLNEAGWGNR PVWTASLPCQ PFSVAGKGFG KSDERHLLPH FVELVRQCKP DTLFGEQVAS
AIRHGWLDDL HAEMGKEGYA VGHCVFGAHS IGTAHIRQRL YWVANSIRTG SQGKVSGRED
EKRQALERLT GCRGADSWMG ITNSNRLKQR SEAAEAARYR NTVDATGGVD SRVEHSKSKQ
MGIPGQSRKR READVVEWLY CRDNKYRPVK SGLKPLVDRT STGVVYSGNQ NQEINADYSL
EAKTMRLRGY GNAIVAGCGI EFISAFMDVM HD
//
