ID   A0A1H3LUY6_9FIRM        Unreviewed;      1264 AA.
AC   A0A1H3LUY6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Hydrophobic/amphiphilic exporter-1, HAE1 family {ECO:0000313|EMBL:SDY67889.1};
GN   ORFNames=SAMN02910414_02115 {ECO:0000313|EMBL:SDY67889.1};
OS   Lachnobacterium bovis DSM 14045.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Lachnobacterium.
OX   NCBI_TaxID=1122142 {ECO:0000313|EMBL:SDY67889.1, ECO:0000313|Proteomes:UP000183918};
RN   [1] {ECO:0000313|EMBL:SDY67889.1, ECO:0000313|Proteomes:UP000183918}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14045 {ECO:0000313|EMBL:SDY67889.1,
RC   ECO:0000313|Proteomes:UP000183918};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNPG01000028; SDY67889.1; -; Genomic_DNA.
DR   RefSeq; WP_074718755.1; NZ_FNPG01000028.1.
DR   AlphaFoldDB; A0A1H3LUY6; -.
DR   STRING; 1122142.SAMN02910414_02115; -.
DR   OrthoDB; 9757876at2; -.
DR   Proteomes; UP000183918; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 2.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 3.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR   Pfam; PF00873; ACR_tran; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183918};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        580..599
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        606..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        632..657
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        677..697
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        709..728
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        766..789
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1104..1123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1130..1150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1156..1181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1202..1223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1235..1259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          200..331
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1264 AA;  139960 MW;  EC4346370C377D93 CRC64;
     MLSKASVKRP YTVLVAVLLV IVIGIVSLSK MTMDLLPNMS FPYVIIVTTS VGSSPKEIET
     NITAPIEASM ATTSNIKEIT SRSSNSYSMV MLEYEQSSNM DSTIIEIQQQ IEQLKSKWDD
     KTSSPIIMQV DPDMLPVMNA AVDVEGLDAN KLSDYINNEV KPSLESVEGV ASVSTSGQLE
     QKVNVYLDQS KIDTLNDKIK QGIEEKFKEA SSKLDSADKE IKNGQNKIED GKKALENTIN
     NTLKQKEELY KKQSDIQNQL EKLIKDRNEL LRIQQTFLTY STSNNFVELE KNVQRLSALN
     EAAQQVGVGN RQELEKQIEE TRKAIEGQNL DIQNRFAALK EIGFNVDDYA SFNEASGKVA
     EDITVLNTQI LTLSTSLGEI LVGTYTTSSI LEVLNSNAAI ASMEMATNSA KLQSAADKIS
     DSKEKIEDTK NSTLSQADLN KVLSMDTLSK ILIAQNFDMP AGYVTDNNVK YLVSVGKKVK
     TVDELENLPL IDMKLDNVSM VRLQDIARIE LTDNSDSTYA RVNEKPGILL AMEKQTGYST
     GDVTKKIKEK FKSLEKENNK LKFTVLMDQG IYIDIIVKSV AQNMIFGAIL AIIVLLIFLR
     DWRTTIIIAF SIPMSVVFAI VLMYFMGITL NIISMSGLAL GIGMLVDNSI VVVENIFRMK
     QETDNIKKAS IVGAKQVSGA IIASTLTTVS VYAPIVFTEG ITRQLFVDLA LTVTFTLVAS
     LIVALTVVPA MSSKMLAKDE EKEIVWFEKI KLKYEAFLGK CLKHKIIVFL VTVLLLVSTF
     FAMISRGMIF MNMEMETNQI SVTISPKRGE TLEFKDLTKK SDAIIERIRK IDGVKTVGAM
     TGGTSASLGI QGIGGSSSIT MYVILNDNNK RSLKDIEKDI HKKTKDMNCN VSTQTSAMDF
     ESFLGSGIAV QIKGKDIEKL QMIAKKTAKI VKKTEGVDYV NDGLKNTMDE FCITIDKEKA
     AEHSFTVAQA YQLVYEVMKN ESPTTTIETD LKDYKVYLVS DKQNKATLED IENLTFKSKD
     LTGNESTIPL KEIASFKKIK TLSTINRDSQ SRYINVSASI DEKHNVSLVS DEISKEIKKL
     KLPEGYTIEM VGEDENIKES MSQLYLMLLL AVIFIYLIMV AQFQSLLSPF IIMFTIPLAF
     TGGFIGLFVT GNELSVIAMI GFIMLAGLIV NNGIVLIDYI NQARESGLEK KEAIISAGLV
     RIRPILMTAL TTILSMSTMA LGIGEGSELM QPMAITIIGG MIYGTLLTLV VEPCIYDIVH
     RKEK
//