ID   A0A1H3M0T7_9PROT        Unreviewed;       559 AA.
AC   A0A1H3M0T7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E {ECO:0000313|EMBL:SDY70173.1};
GN   ORFNames=SAMN05421754_101831 {ECO:0000313|EMBL:SDY70173.1};
OS   Nitrosomonas sp. Nm58.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=200126 {ECO:0000313|EMBL:SDY70173.1, ECO:0000313|Proteomes:UP000199646};
RN   [1] {ECO:0000313|Proteomes:UP000199646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm58 {ECO:0000313|Proteomes:UP000199646};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; FNPQ01000018; SDY70173.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3M0T7; -.
DR   STRING; 200126.SAMN05421754_101831; -.
DR   Proteomes; UP000199646; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016791; F:phosphatase activity; IEA:UniProt.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0044283; P:small molecule biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   Gene3D; 1.20.120.710; Haloacid dehalogenase hydrolase-like domain; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006439; HAD-SF_hydro_IA.
DR   InterPro; IPR041492; HAD_2.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR048764; PylC_PurT_N.
DR   NCBIfam; TIGR01549; HAD-SF-IA-v1; 1.
DR   PANTHER; PTHR46470; N-ACYLNEURAMINATE-9-PHOSPHATASE; 1.
DR   PANTHER; PTHR46470:SF2; N-ACYLNEURAMINATE-9-PHOSPHATASE; 1.
DR   Pfam; PF13419; HAD_2; 1.
DR   Pfam; PF21360; PylC-like_N; 1.
DR   PRINTS; PR00413; HADHALOGNASE.
DR   SFLD; SFLDG01129; C1.5:_HAD__Beta-PGM__Phosphata; 1.
DR   SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199646}.
FT   DOMAIN          120..294
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   559 AA;  62978 MW;  DD3A9DB04CC4B5F7 CRC64;
     MSLRNILVIS GGGFQGLGLI KALRAVTGTR ILVGDCYAEN VARYFSDAFF LLPLIKEEQA
     FLNFVLDLCE RESVNAIFAS TDYELELLAR HRDTFAAQNV TVYVSNIPLL ELANDKLLFY
     RWLLREGLPC LPCYTTHQDT NAAFPLIGKP RHGWGSRGLH ILADRETTSA ISIEENEDLV
     WQPCLKDFDE YSIDFSINVM GNISPLAFRR RIRSLGGFAI LCEPYAPENI QSIARLTIEH
     LIPLGARGPM NLQILRAYDD TCWVSDLNPR AGTSMPLSLA IGLNPLAFLL TDGAVDSNFS
     NHSSVQGSRA RTLRYLEERS IPDLQLNEVR GIVFDLDDTL LDQKAWMISK LELTWHEERA
     VLPERAVFLS MALQIIEEGN RAYLFDALCL QLGLDDTIRL RLIETYRKAR PEDIPLYSDV
     PSTLYQLRKL GYRIAILSDN PPVSQRQKLD VCGLLPLIDT LVLTAELGTQ KPDPHAFIEC
     TRLLELPPDQ IVMVGDNLFR DMRGSFDAGY RHSFHVQRAG AFFNFNPNLA LRVSSVMLTC
     TTITNLNELF WHLTGVATP
//