ID   A0A1H3MEF3_9RHOB        Unreviewed;       446 AA.
AC   A0A1H3MEF3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Zinc protease {ECO:0000313|EMBL:SDY75060.1};
GN   ORFNames=SAMN05444486_103562 {ECO:0000313|EMBL:SDY75060.1};
OS   Lentibacter algarum.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Lentibacter.
OX   NCBI_TaxID=576131 {ECO:0000313|EMBL:SDY75060.1, ECO:0000313|Proteomes:UP000199026};
RN   [1] {ECO:0000313|EMBL:SDY75060.1, ECO:0000313|Proteomes:UP000199026}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24677 {ECO:0000313|EMBL:SDY75060.1,
RC   ECO:0000313|Proteomes:UP000199026};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR   EMBL; FNPR01000003; SDY75060.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3MEF3; -.
DR   STRING; 576131.SAMN05444486_103562; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000199026; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SDY75060.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199026};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..446
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011592846"
FT   DOMAIN          37..181
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          191..373
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   446 AA;  48931 MW;  2D5ABE319BE3FAD2 CRC64;
     MRALLLTLAT SLALAAPAKA DIRDAVTTFT LDNGMDVVVI EDSRAPVVTH MVWYRAGSAD
     EFPGTSGVAH FLEHLLFKGT DTLAPGELSA TVARNGGTDN AFTSYDYTAY FQRVASDRLE
     LMMRLESDRM VNVRLSDDDI LTEREVIIEE RNQRTENSPG ALFREQKNAA QYLNHRYGIP
     VIGWRHEMVT LDLDAALAYY KRFYAPNNAI LVVAGDVTPE AVKALAEQYY GVLEPNPELT
     TRARPAEPPQ TAERRLVFRD ARVAQPYVSR SYLAPERDAG AQREAAALTL LAELLGGGTT
     SYLTERLQFE NQKAVYTAAF YNGESLDDTD FTVLVVPADG VTLPEAEAAM DEAIESFISK
     PIDTDALARI KMQIRASQIY ARDDVGNLAN VYGSALASGL TVQDVQDWPD VLGSITPDEI
     IAAAKSVFNL DHSVTGYLMK EKGDAS
//