ID   A0A1H3NDB8_9PSEU        Unreviewed;       645 AA.
AC   A0A1H3NDB8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Aconitase {ECO:0000313|EMBL:SDY86660.1};
GN   ORFNames=SAMN05216215_103765 {ECO:0000313|EMBL:SDY86660.1};
OS   Saccharopolyspora shandongensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=418495 {ECO:0000313|EMBL:SDY86660.1, ECO:0000313|Proteomes:UP000199529};
RN   [1] {ECO:0000313|EMBL:SDY86660.1, ECO:0000313|Proteomes:UP000199529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDY86660.1,
RC   ECO:0000313|Proteomes:UP000199529};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNOK01000037; SDY86660.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3NDB8; -.
DR   STRING; 418495.SAMN05216215_103765; -.
DR   OrthoDB; 9802769at2; -.
DR   Proteomes; UP000199529; Unassembled WGS sequence.
DR   GO; GO:0003994; F:aconitate hydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR   Gene3D; 3.20.19.10; Aconitase, domain 4; 1.
DR   InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR   InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR   InterPro; IPR015928; Aconitase/3IPM_dehydase_swvl.
DR   InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR   InterPro; IPR006250; Aconitase_put.
DR   InterPro; IPR000573; AconitaseA/IPMdHydase_ssu_swvl.
DR   NCBIfam; TIGR01342; acon_putative; 1.
DR   PANTHER; PTHR43160; ACONITATE HYDRATASE B; 1.
DR   PANTHER; PTHR43160:SF3; ACONITATE HYDRATASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00330; Aconitase; 1.
DR   Pfam; PF00694; Aconitase_C; 1.
DR   PRINTS; PR00415; ACONITASE.
DR   SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
DR   SUPFAM; SSF52016; LeuD/IlvD-like; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          8..407
FT                   /note="Aconitase/3-isopropylmalate dehydratase large
FT                   subunit alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF00330"
FT   DOMAIN          515..579
FT                   /note="Aconitase A/isopropylmalate dehydratase small
FT                   subunit swivel"
FT                   /evidence="ECO:0000259|Pfam:PF00694"
SQ   SEQUENCE   645 AA;  69467 MW;  F8511CC7AFEC77FF CRC64;
     MARNLAHKLI ASHLVDGDLS PGMEVAISID QTLTQDATGT LVMQEIEALG ITRARTEISV
     QYVDHNLLQT DEKNAEDHEF LRSASQRYGL WFSKPGNGVS HPTHMQRFGL PGKTMVGSDS
     HTCAAGSLGM LAIGVGGLEV ALAIAGHPLR VRMPEIWGVR LTGELPPWVS AKDVILEMLR
     RHGVSGGVNR IIEYHGPGLG GLTAMDRHVI ANMGAELGAT TTVFPADSAV RDFLRAESRE
     DDFRTLAADA DAPYDVEEHI DLTTLEPLIA RPSAPDNVVP VREVAGTEIS QVVIGSSANP
     GLRDFAIAAA MVRGRQTDHA VSFDINPTSR EILEDMTRMG ATFDLIAAGA RIHQSGCMGC
     IGMGQAPAVG RNSLRTFPRN FPGRSGTRGD SVWLCSPETA AASALTGVIT DPRDLDQDYP
     ELALPENASV NTAMLVPPLP EEQARAVELV KGTNISALPD FPPLPDRFEA PVLLKAGDNI
     STDEISPAGA SALPLRSNIP ALAEYTFTRI DTDYPRRTRS HPEGHIVVGG HNYGQGSSRE
     HAAITPRYLG LQVVIAKSFA RIHWQNLANF GIVPLEFSEP SDYADIGTDD TLVLDGLRET
     LLTGDELDVR NTTRNRTFRV RHRLSPRQVE AVIAGGVIPL LASRT
//