ID A0A1H3R9C1_9PSEU Unreviewed; 812 AA.
AC A0A1H3R9C1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05216215_105247 {ECO:0000313|EMBL:SDZ21861.1};
OS Saccharopolyspora shandongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=418495 {ECO:0000313|EMBL:SDZ21861.1, ECO:0000313|Proteomes:UP000199529};
RN [1] {ECO:0000313|EMBL:SDZ21861.1, ECO:0000313|Proteomes:UP000199529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDZ21861.1,
RC ECO:0000313|Proteomes:UP000199529};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FNOK01000052; SDZ21861.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3R9C1; -.
DR STRING; 418495.SAMN05216215_105247; -.
DR Proteomes; UP000199529; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 466..799
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 812 AA; 86969 MW; 0EC0454C67C87EE1 CRC64;
MPDHDSSMVR LRGVRVHNLR GVDVDFPRDA LVAVTGVSGS GKSSLAFGTV YAEAQARYLE
SVAPYARRLI DQAGTPDARE ITGLPPAVAF QQARGVAQAR STVGTVTVLS NSLRLLFSRA
GTYPDGAERL DSDAFSPNTP AGACPRCHGL GRIHEVSEAS LVPDPGLSIR EKAIAAWPGA
WQGKNYRDIL AVLGYDVDRP WRELPQAERE WILFTDEQPV VTVHPERTAE RIQRPYQGTY
QSARRYVLHT LATTQSTTLR NRALQYVEVL PCPACDGSGL RPEALAVTFA GATIADLAAL
PLTVLAEKLR AEQDDSVARV VVEDLLARIE ALVELGLGYL AMDRATPTLS AGELQRLRLA
ATLRSTLFGV VYVLDEPSAG LHPDDTQALL RVLDRIRAAG NSLLVVEHEP EIIRHSDWLV
DVGPGAGEHG GLVLYSGPLD GLRTSADSVT RAHLFDPPAP VGKHRTPAGK VELRGVSRHN
LVETDVDFPL GVFTAVTGVS GSGKTTLVTG ILAAAVRDHL GAARSHAGDD EEPVADTSRH
VRSITGLDAI NRLVEVDQRP IGRTPRSNLA TYTGLFDGVR KLFAATDEAR RRKYSAGRFS
FNVDGGRCET CQGEGAVAVE LLFLPSSYSP CPACHGARYN PETLEIRYRD KSIADVLALT
VDDARDFFAD VPAVARSLET LHDVGLSYLT LGQPATELSG GEAQRIKLAT ELQRTRRGHT
LFVLDEPTTG LHPADVEVLM RLLHTLVDAG NTVVVIEHDM TVAAGADHVI DLGPGGGDEG
GSVVAVGAPA EVARAGASRT APYLREVLET AG
//
