ID   A0A1H3RJ76_9RHOB        Unreviewed;       391 AA.
AC   A0A1H3RJ76;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Acetyl-CoA C-acetyltransferase/acetyl-CoA acyltransferase {ECO:0000313|EMBL:SDZ24989.1};
GN   ORFNames=SAMN05444004_108118 {ECO:0000313|EMBL:SDZ24989.1};
OS   Jannaschia faecimaris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Jannaschia.
OX   NCBI_TaxID=1244108 {ECO:0000313|EMBL:SDZ24989.1, ECO:0000313|Proteomes:UP000198914};
RN   [1] {ECO:0000313|EMBL:SDZ24989.1, ECO:0000313|Proteomes:UP000198914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100420 {ECO:0000313|EMBL:SDZ24989.1,
RC   ECO:0000313|Proteomes:UP000198914};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNPX01000008; SDZ24989.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3RJ76; -.
DR   STRING; 1244108.SAMN05444004_108118; -.
DR   OrthoDB; 9764638at2; -.
DR   Proteomes; UP000198914; Unassembled WGS sequence.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR   PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR   PANTHER; PTHR43853:SF22; ACETYL-COA ACETYLTRANSFERASE; 1.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:SDZ24989.1};
KW   Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SDZ24989.1}.
FT   DOMAIN          5..260
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
FT   DOMAIN          269..389
FT                   /note="Thiolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02803"
FT   ACT_SITE        90
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        347
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        377
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ   SEQUENCE   391 AA;  41160 MW;  F88761E9C99C440B CRC64;
     MPDPVIVSLA RTPIGKAGRG AFNQTHGAVM GGHVAAEAVK RAGIEPDLIE DSIWGCGYPE
     YVTGGNIARQ IVLRGGLPDN VAGTTVNRFC ASGLQAIAMG GHMIAQEGAT AILVGGVESI
     SMVQPPARHS RETWLEANRP DLYLPMIETA DIVAKRYNIT RAAQDALGLE SQQRTAAAQD
     AGRFDAEIVP ITVTKAVKDK ETGEVSEEEI TLTMDECNRP STDLAGLEKL QPVRGEGQFI
     TAGNASQLSD GASAMVMMDA AEAVRQGLTP LGAFRGFAVA GCHPDEMGIG PVFAVPRLLE
     RHGLKIEDID LWELNEAFAS QALYCRDTLG IDPSICNVDG GSIAVGHPFG MTGARMTSHL
     MVEGHRRGAK LGVVTMCIGG GQGAAGLFEI F
//