ID   A0A1H3TJD7_9PSEU        Unreviewed;       504 AA.
AC   A0A1H3TJD7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN   ORFNames=SAMN05216215_10844 {ECO:0000313|EMBL:SDZ49921.1};
OS   Saccharopolyspora shandongensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=418495 {ECO:0000313|EMBL:SDZ49921.1, ECO:0000313|Proteomes:UP000199529};
RN   [1] {ECO:0000313|EMBL:SDZ49921.1, ECO:0000313|Proteomes:UP000199529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDZ49921.1,
RC   ECO:0000313|Proteomes:UP000199529};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC       ECO:0000256|RuleBase:RU003345}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNOK01000084; SDZ49921.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3TJD7; -.
DR   STRING; 418495.SAMN05216215_10844; -.
DR   OrthoDB; 6882680at2; -.
DR   Proteomes; UP000199529; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR   CDD; cd07099; ALDH_DDALDH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR036492}.
FT   DOMAIN          17..470
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        250
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU10007"
FT   ACT_SITE        284
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ   SEQUENCE   504 AA;  53381 MW;  D517FF8AC0AC517F CRC64;
     MTQTARGSVE MPSGTTEQSP TFESIDPRTG EIVGRHPIHD AAEVGARVIA AREAQAAWAE
     LGFAGRKQRL DAWRKLLAKR LDELAGVICA ETGKPLDDAK LELMLVVDHL HWAASNAEKV
     LRRRKVSAGI VMANQTATVE YLPFGVIGVI GPWNYPAFTP MGSIAYALAA GNAVVFKPSE
     LTPGVGQWLT ESFAEAVPEH PVFQLVTGFG ETGAALCAAG VDKVAFTGST ATGKRVMASC
     AENLVPVLVE CGGKDALIVD ADADLAAAAD AAVWGAMSNA GQTCIGVERV YVVDAVADRF
     LEMVAERAAK LRPGGEPGAN FGPITMPSQV DIIRGHIDDA LSRGGRAVVG GEHSVRPPFV
     EPVVLTDVPE DSTAITEETF GPTIVVQRVR DADEGVARAN NSRYGLGASV FSRARGVELA
     RQLRTGMVAV NSVIAFAGVP SLPFGGVGDS GFGRIHGADG LREFTRPQSV TRLRYRMPLN
     PMSFARAKGT VRRLVRVVRL VRGR
//