ID   A0A1H3VL86_9BACI        Unreviewed;       327 AA.
AC   A0A1H3VL86;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Regulatory protein MsrR {ECO:0000256|ARBA:ARBA00040752};
GN   ORFNames=SAMN05421743_10148 {ECO:0000313|EMBL:SDZ74898.1};
OS   Thalassobacillus cyri.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Thalassobacillus.
OX   NCBI_TaxID=571932 {ECO:0000313|EMBL:SDZ74898.1, ECO:0000313|Proteomes:UP000198584};
RN   [1] {ECO:0000313|EMBL:SDZ74898.1, ECO:0000313|Proteomes:UP000198584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCM7597 {ECO:0000313|EMBL:SDZ74898.1,
RC   ECO:0000313|Proteomes:UP000198584};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in SarA attenuation. Affects resistance to oxacillin
CC       and teicoplanin, as well as the synthesis of virulence factors.
CC       {ECO:0000256|ARBA:ARBA00037178}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC       Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
CC   -!- SIMILARITY: Belongs to the LytR/CpsA/Psr (LCP) family.
CC       {ECO:0000256|ARBA:ARBA00006068}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNQR01000001; SDZ74898.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3VL86; -.
DR   STRING; 571932.SAMN05421743_10148; -.
DR   OrthoDB; 9782542at2; -.
DR   Proteomes; UP000198584; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.630.190; LCP protein; 1.
DR   InterPro; IPR004474; LytR_CpsA_psr.
DR   NCBIfam; TIGR00350; lytR_cpsA_psr; 1.
DR   PANTHER; PTHR33392; POLYISOPRENYL-TEICHOIC ACID--PEPTIDOGLYCAN TEICHOIC ACID TRANSFERASE TAGU; 1.
DR   PANTHER; PTHR33392:SF8; REGULATORY PROTEIN MSRR; 1.
DR   Pfam; PF03816; LytR_cpsA_psr; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198584};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          91..236
FT                   /note="Cell envelope-related transcriptional attenuator"
FT                   /evidence="ECO:0000259|Pfam:PF03816"
SQ   SEQUENCE   327 AA;  37211 MW;  E4E0FD070A8664A4 CRC64;
     MTTRKEYKQK NRKKKRKRKV FIAVALIFLL IGIGISSYEY MAGKRDAMGE SEGELENSEF
     KDEFQGVDNK DGKTTVLMLG VDKRSNKETM RTDTIMIAQY DPEENEAKLA SLMRDTYVDI
     PGYGYNKLNA AFAFGGPELL RQTIKKNFGI ETEYYSIVDF DGFKQIVDTV APEGIKVDVE
     KKMYYKDNAG TINLEPGTQK LNGEELLGYA RYRGDAFSDF GRVKRQQEVI QLMKDELVSA
     KGLLKVPRLI GTLQPYIDTN IDSGKMVGLG KDFIFNAPDN IDTLRVPVEG SYWDERYSHA
     GAVLAHDEKK NREALQEFFQ LEDKTTE
//