ID   A0A1H3VLM2_9RHOB        Unreviewed;       354 AA.
AC   A0A1H3VLM2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE            EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN   ORFNames=SAMN05444370_101192 {ECO:0000313|EMBL:SDZ75703.1};
OS   Rubrimonas cliftonensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Rubrimonas.
OX   NCBI_TaxID=89524 {ECO:0000313|EMBL:SDZ75703.1, ECO:0000313|Proteomes:UP000198703};
RN   [1] {ECO:0000313|EMBL:SDZ75703.1, ECO:0000313|Proteomes:UP000198703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15345 {ECO:0000313|EMBL:SDZ75703.1,
RC   ECO:0000313|Proteomes:UP000198703};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC         methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC         ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR   EMBL; FNQM01000001; SDZ75703.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3VLM2; -.
DR   STRING; 89524.SAMN05444370_101192; -.
DR   OrthoDB; 9790967at2; -.
DR   Proteomes; UP000198703; Unassembled WGS sequence.
DR   GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR045004; ECH_dom.
DR   InterPro; IPR032259; HIBYL-CoA-H.
DR   PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR   Pfam; PF16113; ECH_2; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SDZ75703.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198703}.
FT   DOMAIN          13..342
FT                   /note="Enoyl-CoA hydratase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF16113"
SQ   SEQUENCE   354 AA;  37061 MW;  ECC183AC947FABDD CRC64;
     MDDIIFERRG GLGLVTLNRP KALNALTHAM ALALDARLRD WRDDAGVQAV AIVGAGERAF
     CAGGDVRALW EAGRGDPARD GARNWRFYAD EYRLNALIHR YQKPYVAFMD GIVMGGGVGV
     SIHGARRVSG DATLFAMPET GIGLFPDVGA TWFLPRLPGE TGMWLGLTGA RLKAADAGAA
     GLCDLHVPSA AQAAAVEALA AADLSAGLAA VDAALAPFAA DPGPANLPRL RADIDRLFSG
     GGVEAVLAAL DGDGGEWAAE QAAAIRAKSP SSTRIAFRQL REGRALDFAA CMALEYRLAR
     FCMVSPDFYE GVRAVVIDKD AAPRWRPSAL AEADDAHVAG AFAPAPAGEE LALD
//