ID   A0A1H3WET6_9FIRM        Unreviewed;       289 AA.
AC   A0A1H3WET6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=23S rRNA (Cytosine1962-C5)-methyltransferase {ECO:0000313|EMBL:SDZ84914.1};
GN   ORFNames=SAMN02745687_00748 {ECO:0000313|EMBL:SDZ84914.1};
OS   Lachnospiraceae bacterium NK3A20.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=877406 {ECO:0000313|EMBL:SDZ84914.1, ECO:0000313|Proteomes:UP000199449};
RN   [1] {ECO:0000313|EMBL:SDZ84914.1, ECO:0000313|Proteomes:UP000199449}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NK3A20 {ECO:0000313|EMBL:SDZ84914.1,
RC   ECO:0000313|Proteomes:UP000199449};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNQX01000010; SDZ84914.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3WET6; -.
DR   OrthoDB; 9805492at2; -.
DR   Proteomes; UP000199449; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR019614; SAM-dep_methyl-trfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43042:SF2; SAM-DEPENDENT METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF10672; Methyltrans_SAM; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SDZ84914.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199449};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDZ84914.1}.
FT   DOMAIN          37..202
FT                   /note="S-adenosylmethionine-dependent methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF10672"
SQ   SEQUENCE   289 AA;  32781 MW;  EE8FFB01AB85C4D9 CRC64;
     MWTADNWKDY EVLDTSSGEK LERWGEYRLI RPDPQVIWTT EKSKDWKNVN GHYYRSSKGG
     GNWEFHQLPE EWMITYKDRR FMLKPFSFKH TGLFPEQAVN WDWFMPIIEA AVQAGRKVKV
     LNLFAYTGGA TLAAAAAGAA VTHVDASKGM VTWAKENAEL SGLAEAPIRW LVDDCTRFVE
     REIRRGNRYD AIILDPPSYG RGPKGEIWKI EDNIFDFLNL IRGILVEKPL FVLLNSYTTG
     LQPAVLSYLL HEALDPLCKG NVDADEVGLR VKSTGLVLPE GAAGRWTPC
//