ID   A0A1H3WIZ9_9FIRM        Unreviewed;       446 AA.
AC   A0A1H3WIZ9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=GTPase, G3E family {ECO:0000313|EMBL:SDZ87093.1};
GN   ORFNames=SAMN05216349_10251 {ECO:0000313|EMBL:SDZ87093.1};
OS   Oribacterium sp. KHPX15.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Oribacterium.
OX   NCBI_TaxID=1855342 {ECO:0000313|EMBL:SDZ87093.1, ECO:0000313|Proteomes:UP000199483};
RN   [1] {ECO:0000313|EMBL:SDZ87093.1, ECO:0000313|Proteomes:UP000199483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KHPX15 {ECO:0000313|EMBL:SDZ87093.1,
RC   ECO:0000313|Proteomes:UP000199483};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR   EMBL; FNRG01000002; SDZ87093.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3WIZ9; -.
DR   Proteomes; UP000199483; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199483}.
FT   DOMAIN          358..446
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
FT   REGION          238..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..289
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   446 AA;  51279 MW;  6EE18A51F8B74E1D CRC64;
     MTSIDIVSGF LGAGKTTFIQ RLLDEALKTE KVVLIENEFG EIGIDSGFLK DSGIEIREMN
     QGCICCSLVG NFEQSLTEVV NTYKPDRIII EPSGVGKLSD IIGAVKSVSE SLDVELHAAV
     TVVDAKKAKM YSKNFGEFFN NQIEYAGTVV LSRTDIADEA KVGEAVSIIK GINERATVIT
     TPADKLTGEQ LVNIISKKYD LAEEMLQDVM ERVHEHEDHE HEDEHDEVET LPNGVQIHHS
     HSHHHHHHHD HDEHEHEHHH HDHEEHEHHH DHDEDEHEHH HHDEDEHEHH HHEDGEECCC
     HHDHEEHEHH HHHEDGEECC CHHDHEEHEH HHHDHDHEHE HHHEGCSCGH DHDADEIFKT
     WGVETPYPFE KDKLSQILEE MAHSEKYGKV VRCKGMLPTK DGEWMYFDLV PEQTEIRTGS
     PEYTGKVVVI GADLNEHELR EAFAGM
//