ID A0A1H3XGS1_9GAMM Unreviewed; 567 AA.
AC A0A1H3XGS1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Potassium/proton antiporter, CPA1 family {ECO:0000313|EMBL:SDZ98625.1};
GN ORFNames=SAMN02745729_101148 {ECO:0000313|EMBL:SDZ98625.1};
OS Marinobacterium iners DSM 11526.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinobacterium.
OX NCBI_TaxID=1122198 {ECO:0000313|EMBL:SDZ98625.1, ECO:0000313|Proteomes:UP000242469};
RN [1] {ECO:0000313|Proteomes:UP000242469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11526 {ECO:0000313|Proteomes:UP000242469};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNRJ01000001; SDZ98625.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3XGS1; -.
DR STRING; 1122198.SAMN02745729_101148; -.
DR OrthoDB; 9810759at2; -.
DR Proteomes; UP000242469; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022538};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000242469};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022449}.
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 400..481
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 567 AA; 61315 MW; 1BB034A724DF1B39 CRC64;
MILTLLFASA MLLISILLSP LSNRIGMPVL LLFLGVGLLA GQTQMGQNLS ADVESTFFVG
HLALAIILLD GGMRTRIETF RVGLRPALAL ATFGVVITAA VTGLAAWWIL ELPLLHALLI
GTIISSTDAA AVFALLQNHG LRLNQRVSAT LEIESGSNDP MAIFLTIILL ELITRDTPPG
VAEAALLLGK QLALGALGGL AGGWAMARLL PRLDLQPAFY PLLVTAAGLT VFSVVYLLDG
SGFLAIYLMG ILIGNRGLRK LDDILQVHDG LAWLAQLSLF LMLGLLLSPH DKLAFVPEGI
ALGAVLILLA RPLSIALTLW PFGFRWREQL FIAWVGLRGA VPIVLALFPL MAGLDNAALF
PTIAFIVVIM SLLLQGTTLA RVARWLKLEL PAEPEAMRRL SLEWSMEQNH RVWVFELDGE
HWTPARTLQG VKLPGNIVIS AVLRGRELLP WTSELKLQSG DRLAVIGNDE AEKPLARLFS
SVESIPALKE RTFFGAFELN ANIELAALAQ NFGVAVPPDQ AEQQLSEYIR ERLHTAPVVG
DRVPLGAIEL VVKAVEAGQV TRVGLKF
//
