ID A0A1H3XYD2_9FIRM Unreviewed; 511 AA.
AC A0A1H3XYD2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SEA04250.1};
GN ORFNames=SAMN05216349_10411 {ECO:0000313|EMBL:SEA04250.1};
OS Oribacterium sp. KHPX15.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Oribacterium.
OX NCBI_TaxID=1855342 {ECO:0000313|EMBL:SEA04250.1, ECO:0000313|Proteomes:UP000199483};
RN [1] {ECO:0000313|EMBL:SEA04250.1, ECO:0000313|Proteomes:UP000199483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KHPX15 {ECO:0000313|EMBL:SEA04250.1,
RC ECO:0000313|Proteomes:UP000199483};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; FNRG01000004; SEA04250.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3XYD2; -.
DR Proteomes; UP000199483; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF7; SODIUM_PROTON-DEPENDENT ALANINE CARRIER PROTEIN YRBD-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000199483};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 165..186
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 211..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 241..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 386..410
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 422..445
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 511 AA; 55542 MW; F01D5959AD992815 CRC64;
MEGLLAFISA VCSRIQTVSD LFWDFPTNFE WYRGIPVLGN FSLAIILLIG SGIYFSVNLR
FIQLRRFRYG IRVLKNSKAK TGITPLASFF LSTAMRVGPG NILGVTGAVS VGGPGALLWM
WISAFFGMAT AYVESTLSQI FKEKKDDEYL GGMSFYGRRL LKNSAIVGVV LSMMYIIYAI
LCFPAQGFNT VSAMGQIASI VSGYDLPTTH AVYWIGFLVV ILATCAVSFG GTKKISKVTD
VLVPVMAVVY VITVLILIFI NISRIPWFFY AVFTQAFKPE AIFGGAFGTA LMQGVKRGLM
SNEAGQGTIT MPAAASDAAH PCDQGCVQAI GVFLDTIVIC TLTGFVVIMG RAWLTENGAA
WMDLGKLPKY LASIEELTPG IGLNSVVTLL VSLCFGLFAF TCLLGFMSFS EICANRISRS
KVFINAIRII DIAVICFGML TSIVGLDLGA LWDLSDFANI LIAYCNIPLL YIGFKYVKKA
TVHFESKHDT PFSSAVIGVD VPVWDDKARA N
//
