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Entry: A0A1H3YJR4_9GAMM
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ID   A0A1H3YJR4_9GAMM        Unreviewed;       348 AA.
AC   A0A1H3YJR4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   08-MAY-2019, entry version 9.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN02982996_01002 {ECO:0000313|EMBL:SEA11192.1};
OS   Lonsdalea quercina.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Lonsdalea.
OX   NCBI_TaxID=71657 {ECO:0000313|EMBL:SEA11192.1, ECO:0000313|Proteomes:UP000187280};
RN   [1] {ECO:0000313|EMBL:SEA11192.1, ECO:0000313|Proteomes:UP000187280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29281 {ECO:0000313|EMBL:SEA11192.1,
RC   ECO:0000313|Proteomes:UP000187280};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; FNQS01000002; SEA11192.1; -; Genomic_DNA.
DR   RefSeq; WP_026742684.1; NZ_FNQS01000002.1.
DR   STRING; 1082705.JIBP01000010_gene268; -.
DR   GeneID; 33076137; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000187280; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000187280};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187280};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       43    337       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   348 AA;  37929 MW;  1B2013B44A9600F1 CRC64;
     MPQTDELRSS RLDTLITPEQ LIGALPLTPD VAETVTTARS NIENILSGRD PRLLVIIGPC
     SLHDPESALA YARRLAELRT RHQHRLEIVM RAYFEKPRTV VGWKGLIADP DLNGSFQVNK
     GLTLARQLLL EINKLGLPAA TEFLDIVTGQ YIADLISWGA IGARTTESQI HREMASALSC
     PVGFKNGTDG NIRIAIDAIR SAQASHMFLS PDKQGRMSVY RSSGNPYGHM IMRGGKTPNY
     HAEDVAQACQ QLASFSLTPR LIIDCSHGNC QKQHRRQSDV ALSVCGQIAE GTTAIAGVMI
     ESFLVEGAQP SLNPASLTFG QSITDPCLGW EDSERVLAQL AEAVSHRL
//
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