ID A0A1H3Z589_9BURK Unreviewed; 438 AA.
AC A0A1H3Z589;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Nucleobase:cation symporter-1, NCS1 family {ECO:0000313|EMBL:SEA18442.1};
GN ORFNames=SAMN05192564_101585 {ECO:0000313|EMBL:SEA18442.1};
OS Paraburkholderia sartisoli.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=83784 {ECO:0000313|EMBL:SEA18442.1, ECO:0000313|Proteomes:UP000198638};
RN [1] {ECO:0000313|EMBL:SEA18442.1, ECO:0000313|Proteomes:UP000198638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 24000 {ECO:0000313|EMBL:SEA18442.1,
RC ECO:0000313|Proteomes:UP000198638};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNRQ01000001; SEA18442.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3Z589; -.
DR STRING; 83784.SAMN05192564_101585; -.
DR OrthoDB; 5444231at2; -.
DR Proteomes; UP000198638; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015209; F:cytosine transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR030191; CodB.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR InterPro; IPR012732; Thia_CytX.
DR NCBIfam; TIGR02358; thia_cytX; 1.
DR PANTHER; PTHR30569:SF0; CYTOSINE PERMEASE; 1.
DR PANTHER; PTHR30569; CYTOSINE TRANSPORTER CODB; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000198638};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 438 AA; 45879 MW; C771149D5FE7158B CRC64;
MANDPVSGEA GSTYAPLTPV PDSRRAFRTG DAFALWFSLG IGLLVAQAGA LLVPGLSLPH
ALAAIVIGSV IGVVLLALAG VIGTDTGLAA MSSLRPTLGV RGASVPAVLN AVQLVGWGSF
EIIVMRDSAD ALARQSFGLS MPLAWTVIFG VLATLLAISG PLSFVRRFLR TWGIWLLLAG
ALWLTWNLLA KHDLAALMQR PGTGEMPFGG AIDLVVAMPL SWLPLIADYT RFGRRAGETF
RGTLLGYGIA NIWFYALGAI YGLAAGGGDA LLTTALAQAG GGLALLLILI DEIDNAFADI
HSAAVSTGTF WTRMSVPLLS ASFGAVCTLI ALAVPMAKYQ NFLLLIGSVF APLFGVVLVD
HFIVRKRRID AAAIGDVRGR YGFSGGWHVS AFIAWAIGIA AYQAINQWLP NLGATLPALA
IGALCYLAFV SARREAYA
//
