ID A0A1H3ZTW7_9GAMM Unreviewed; 408 AA.
AC A0A1H3ZTW7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=General secretion pathway protein F {ECO:0000256|ARBA:ARBA00030750};
GN ORFNames=SAMN02982996_01314 {ECO:0000313|EMBL:SEA27157.1};
OS Lonsdalea quercina.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Lonsdalea.
OX NCBI_TaxID=71657 {ECO:0000313|EMBL:SEA27157.1, ECO:0000313|Proteomes:UP000187280};
RN [1] {ECO:0000313|EMBL:SEA27157.1, ECO:0000313|Proteomes:UP000187280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29281 {ECO:0000313|EMBL:SEA27157.1,
RC ECO:0000313|Proteomes:UP000187280};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the type II secretion system inner membrane
CC complex required for the energy-dependent secretion of extracellular
CC factors such as proteases and toxins from the periplasm.
CC {ECO:0000256|ARBA:ARBA00002684}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU003923}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU003923}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GSP F family.
CC {ECO:0000256|ARBA:ARBA00005745, ECO:0000256|RuleBase:RU003923}.
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DR EMBL; FNQS01000003; SEA27157.1; -; Genomic_DNA.
DR RefSeq; WP_026743519.1; NZ_FNQS01000003.1.
DR AlphaFoldDB; A0A1H3ZTW7; -.
DR STRING; 71657.SAMN02982996_01314; -.
DR eggNOG; COG1459; Bacteria.
DR Proteomes; UP000187280; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR011850; T2SS_GspF.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR NCBIfam; TIGR02120; GspF; 1.
DR PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR PANTHER; PTHR30012:SF0; TYPE II SECRETION SYSTEM PROTEIN F-RELATED; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000187280};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003923};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003923}.
FT TRANSMEM 172..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..196
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
FT DOMAIN 277..398
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
SQ SEQUENCE 408 AA; 44651 MW; C5EF55A62A48D73E CRC64;
MALFHYQALS AQGKRRRGVQ EADSARQARQ LLREKGLVAL TLEAQRDAGP SGDGGFFTLR
RSQRIGACDL ALLTRQLATL VAAALPLEEA LAAVAEQSEK AALRTLMAAV RAKVVEGHSL
AEALSSFPGS FERLYCAMVA AGEASGHLDI VLNRLADYTE QRQQMRSRIQ QAMIYPCVLT
LVAIAVVCIL LSAVVPKVVD QFVHMKQALP FSTRLLMGIS DAVRVGGPWV LLLLALGMMT
GRWLLRQEKY RLPFHRFLLR LPVVGRVLRG LNTARYARTL SILNASAVPL LQAMRISGDV
LSNDDARERL THATEAVREG VSLHQALQQT SLFPPMMRHM IASGERSGDL DAMLARAADN
QDREFSAQVT LALGLFEPLL VVTMAGVVLF IVLAILQPIL QLNTLMSM
//
