ID A0A1H3ZZK0_9GAMM Unreviewed; 400 AA.
AC A0A1H3ZZK0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:SEA29289.1};
GN ORFNames=SAMN05660964_01282 {ECO:0000313|EMBL:SEA29289.1};
OS Thiothrix caldifontis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Thiothrix.
OX NCBI_TaxID=525918 {ECO:0000313|EMBL:SEA29289.1, ECO:0000313|Proteomes:UP000199397};
RN [1] {ECO:0000313|EMBL:SEA29289.1, ECO:0000313|Proteomes:UP000199397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21228 {ECO:0000313|EMBL:SEA29289.1,
RC ECO:0000313|Proteomes:UP000199397};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FNQP01000006; SEA29289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3ZZK0; -.
DR STRING; 525918.SAMN05660964_01282; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000199397; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000199397};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..400
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011444999"
FT DOMAIN 52..293
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 380..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 168..195
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 384..400
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 42342 MW; 172CD28B57155DA6 CRC64;
MTIRKKASVL LIAGLFASTF AVQAAEIIQV ETAGARSQSV LGSTVIPYKE VTLSAQIPGV
VKYVAGAVGT NLTEGAVVFK IDEAQLMAKR NAVVAQISIA QTGVQNAQAQ YYRELTSPRS
KDVGAMPGFG MPSMFDRMAV RPFAESFMGG YDSDTIRQGD LTNAMSAVSQ AQGQLQQAMS
QLQEIDSALR DASALAPFEG IILEKMVEVG DTVQPGQPLV KYGYVKYKRL QADVPSGLVG
NLSKDMLLPA RIDGSTDTSV RVSEIYPIAD PSRHTVTVKF DIPMEITTAP GMYAEIYVPE
NKKGGSQVTV IPRSALMKGS SLPGVLVVKD DNTSELRMVR LGAEQNGGSK VAVISGLNPG
EKIINNPPTG VTSGWMPTTV NPTPVNSTPT PAPVPSPPAK
//
