ID A0A1H4A293_9GAMM Unreviewed; 456 AA.
AC A0A1H4A293;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Two-component system, NarL family, sensor kinase {ECO:0000313|EMBL:SEA29632.1};
GN ORFNames=SAMN02745729_102236 {ECO:0000313|EMBL:SEA29632.1};
OS Marinobacterium iners DSM 11526.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinobacterium.
OX NCBI_TaxID=1122198 {ECO:0000313|EMBL:SEA29632.1, ECO:0000313|Proteomes:UP000242469};
RN [1] {ECO:0000313|Proteomes:UP000242469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11526 {ECO:0000313|Proteomes:UP000242469};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNRJ01000002; SEA29632.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4A293; -.
DR STRING; 1122198.SAMN02745729_102236; -.
DR OrthoDB; 9797605at2; -.
DR Proteomes; UP000242469; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR033480; sCache_2.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR017171; Sig_transdc_His_kinase_MctS.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PIRSF; PIRSF037314; STHK_MctS; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEA29632.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242469};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..451
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 456 AA; 51754 MW; 186E6AF17D2CB8CE CRC64;
MPLKIKILLL SILPMMLVTS AVAWLGMNQA RQLSEEEIRL FEQHLLGSKQ RELENYVSLA
LTSIAHIVDT AGPDDAQAKS AVKQILTDMT FGDDQDGYFF VYTLEGVNLV HPTQPELVGQ
DLYDMQDARG NYVIRNLLER ARQGGGFHRY LWEKPSKQAR EEKISYAVML PKWNWMLGTG
LYLDDISREV AKIRAEVNRN IRNTFFTVLV IMSVAVVLVV LLGVAINLHE NRLADSRLRL
LAHRSILANV ADRRRFSREL HDGINQLMVS VLYRIELAQR KLKQGNQEGL TDLDKGYQVL
NEAIQEVRRI SHDLRPTLLD DLGLEAALEG LLDRFTERTG IRLDLDIRLP GGRLPEDVEI
TVYRLVQEGL TNVERHSGAG LLRLRLWQQS GQLWLKMQDD GCGFDPEVLE RFEGIGLRNM
RERVELLGGE FRLASRQGQG ATLLAGLSLQ QTGGER
//
