ID A0A1H4AAG3_9GAMM Unreviewed; 445 AA.
AC A0A1H4AAG3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=HlyD family secretion protein {ECO:0000313|EMBL:SEA32975.1};
GN ORFNames=SAMN05660964_01386 {ECO:0000313|EMBL:SEA32975.1};
OS Thiothrix caldifontis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Thiothrix.
OX NCBI_TaxID=525918 {ECO:0000313|EMBL:SEA32975.1, ECO:0000313|Proteomes:UP000199397};
RN [1] {ECO:0000313|EMBL:SEA32975.1, ECO:0000313|Proteomes:UP000199397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21228 {ECO:0000313|EMBL:SEA32975.1,
RC ECO:0000313|Proteomes:UP000199397};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FNQP01000006; SEA32975.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4AAG3; -.
DR STRING; 525918.SAMN05660964_01386; -.
DR OrthoDB; 9791520at2; -.
DR Proteomes; UP000199397; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.20.50.140; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199397};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..324
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 364..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 134..202
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 445 AA; 46231 MW; 5F229FD2C9624FEF CRC64;
MSNPINSTTT DSVKAVLAAG GKKKSQGSKG KWLLALLVAG IVAGGTGYYF MGQSQTKSQA
SYKTTPAKTG NLSVTVTATG NLQPKNQVDI GTELSGTVDD VLVDANEVVK KGQKLASLNT
AQLQDTITKG KASLASAQAK VKQTAASVKE ARTKLNRLRE LYKASGGKLP AKSEIDAAEA
TLERAQADAE VAKTTVTSAT AELRSSETNL GKAIITSPIN GVVLTRTVEP GQTVASSLSA
PTLFTLAEDL AQMEVEVGVD EADVGQVKAG QKAEFSVDAW PGRKYPAEIT RVSLGADTSE
NVVSYLTVLA VQNTDLTLRP GMTATATIKT ESRENVLLIP NTALRFSPPV ATVPAAANAN
SSFLSKLMPR PPGMGGQRKR TNGTSPTPSP DGMQKIWVLD NNTPVAVEVK TGISDGKQTE
IVSGDLKEGM AVITESTGGT TGGKQ
//
