ID A0A1H4AE14_9FIRM Unreviewed; 469 AA.
AC A0A1H4AE14;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family {ECO:0000313|EMBL:SEA34160.1};
GN ORFNames=SAMN02745687_02569 {ECO:0000313|EMBL:SEA34160.1};
OS Lachnospiraceae bacterium NK3A20.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=877406 {ECO:0000313|EMBL:SEA34160.1, ECO:0000313|Proteomes:UP000199449};
RN [1] {ECO:0000313|EMBL:SEA34160.1, ECO:0000313|Proteomes:UP000199449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NK3A20 {ECO:0000313|EMBL:SEA34160.1,
RC ECO:0000313|Proteomes:UP000199449};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNQX01000060; SEA34160.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4AE14; -.
DR OrthoDB; 9782387at2; -.
DR Proteomes; UP000199449; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21128; SPASM_rSAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43524; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43524:SF1; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199449};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 107..318
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 469 AA; 53412 MW; FD447FB6CE9E4D40 CRC64;
MASLGHAAER KLFEVAIDAA FNHVDKDREK AMIQFIDLMQ KILGNTWQPE AFDALRGIYE
NPDSKWCRFT NDLFDNIDHK QLKNAALNLG YEAAFRGYKN TQANAKKYGC NIPWIILFDP
TSACNLHCTG CWAAEYGHQM NLSYEDMDKI VTEGEELGIH AYLMTGGEPT VRIRDIWKLC
EAHPHSFFSA FTNGTLIDDE FCENMLRLGN FTVNISVEGF RETNDGRRGS GDFDKVMKAM
DCLKAHKLAF GTSICYTSVN YKVVTSDDFL DMLIEHGVKW AWYFHYMPVG NAASTDLLLN
PEQREYMYHR VREIRGFEGG KPLFTMDFQN DGEFIHGCIA GGRVYCHINP HGDVEPCVFI
HYSNANIHDK SLLECLQQPL FKAYQANQPF NENHLQPCPM LENPEVLRQL VADTDAKSTD
MESKEDVNHL CGKCDPYAAS WAPVADRLWK GNHPGFENEP REVQHVSGE
//
