ID   A0A1H4AS72_9BACT        Unreviewed;       314 AA.
AC   A0A1H4AS72;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:SEA38743.1};
GN   ORFNames=SAMN05660909_01743 {ECO:0000313|EMBL:SEA38743.1};
OS   Chitinophaga terrae (ex Kim and Jung 2007).
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=408074 {ECO:0000313|EMBL:SEA38743.1, ECO:0000313|Proteomes:UP000199656};
RN   [1] {ECO:0000313|Proteomes:UP000199656}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23920 {ECO:0000313|Proteomes:UP000199656};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; FNRL01000006; SEA38743.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4AS72; -.
DR   STRING; 408074.SAMN05660909_01743; -.
DR   OrthoDB; 9796205at2; -.
DR   Proteomes; UP000199656; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365}.
FT   ACT_SITE        137
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        165
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
SQ   SEQUENCE   314 AA;  35515 MW;  BCB693FAD33DC4F7 CRC64;
     MQKKFVPVMI TPFNLKAQID LGMVEALVDF YLEAGVEGFF ANCLSSEMYS ISEDERLELT
     QHVVRYVNGR VPVVATGSFG LTINDKAEFT KKIYDTGVDS VIMITGHFAN VDEPDDILLK
     RFDQLFSLTG DIPLGLYECP APYKRIITPA ILKTLLATNR LIYHKDTSCN VEQVKAKLDV
     VKGSRLEFYD AHTPNAVASM QMGAAGMSSI SGNFYPEILV WLCKNVLEED KQEDVRWIQS
     ELQRVDPLIH IAYPMSAKYF LQQRGFPVRT ISRAHALELT PEQKQTLQQI HRDFLGWCER
     LQIQPVQAAA LPSH
//