ID   A0A1H4CDR3_ALKAM        Unreviewed;       378 AA.
AC   A0A1H4CDR3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE            EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN   ORFNames=SAMN04488051_104109 {ECO:0000313|EMBL:SEA58433.1};
OS   Alkalimonas amylolytica.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alkalimonas.
OX   NCBI_TaxID=152573 {ECO:0000313|EMBL:SEA58433.1, ECO:0000313|Proteomes:UP000198773};
RN   [1] {ECO:0000313|EMBL:SEA58433.1, ECO:0000313|Proteomes:UP000198773}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.3430 {ECO:0000313|EMBL:SEA58433.1,
RC   ECO:0000313|Proteomes:UP000198773};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC         mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:68623; EC=5.1.3.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00036080};
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR   EMBL; FNRM01000004; SEA58433.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4CDR3; -.
DR   STRING; 152573.SAMN04488051_104109; -.
DR   OrthoDB; 9803238at2; -.
DR   Proteomes; UP000198773; Unassembled WGS sequence.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198773}.
FT   DOMAIN          23..369
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   378 AA;  41858 MW;  96ED2D0E13958B3C CRC64;
     MLKTLIVFGT RPEAIKMAPL VNTLQQTPGI ENKVCVTAQH RQMLDQVLGL FDIKPDFDLD
     IMKPGQDLFD VTITILQRLK AVLRSYQPDL VLVHGDTSTT FATALACYYE KIAIGHVEAG
     LRTGNLFSPW PEEANRKLTG VLTQLHFAPT ESARQNLLSE GVVPEQISVT GNTVIDALLA
     VVGKIEQTPA LLQELSEQLP WGQERRMVLI TGHRRESFGA GFDNICAALK QLADTYPDCD
     FVYPVHLNPN VREPVFRLLG EQANIHLIEP QDYLPFVFLM RQSYLVLTDS GGIQEEAPSL
     GKPVLVMRDT TERPEAVAAG TVLLVGTDQD SIVREVSRLM DDAAWYQQMS VAHNPYGDGS
     ACQQIAERLL HYPAVSKG
//