ID A0A1H4DQG5_9SPHI Unreviewed; 631 AA.
AC A0A1H4DQG5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=SAMN05443550_10560 {ECO:0000313|EMBL:SEA75013.1};
OS Pedobacter hartonius.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=425514 {ECO:0000313|EMBL:SEA75013.1, ECO:0000313|Proteomes:UP000198850};
RN [1] {ECO:0000313|EMBL:SEA75013.1, ECO:0000313|Proteomes:UP000198850}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19033 {ECO:0000313|EMBL:SEA75013.1,
RC ECO:0000313|Proteomes:UP000198850};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNRA01000005; SEA75013.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4DQG5; -.
DR STRING; 425514.SAMN05443550_10560; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000198850; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198850}.
FT DOMAIN 9..64
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 66..452
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 514..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 631 AA; 70323 MW; 8AF91D34A2CF7A6C CRC64;
MQIKSLAEYE ETYRFSVEWP EKFWAGIAEN FLWRKKWDKV LSWNFTEPNI KWFEGAKLNI
TENCLDRHLA KNGDKPAIIW ESNDPEKSSI TLTYKVLHEQ VCRFANVLKK NGVVKGDRIC
IYMPMVPELA VAVLACARIG AVHSVIFGGF SAKSIADRIN DSACKLVITA DGSFRGNKQI
QLKEVIDDAL IGCPTVEKVI VLTHTRTPVS MLKGRDLWFE DEIKQVDTHC PAEEMDAEDM
LFILYTSGST GKPKGVVHTV GGYMVYAGYT FSNAFNYQPD EVFFCTADIG WITGHSYIVY
GPLSQGATTL MFEGVPTYPT PSRLWEVIEK HKVNILYTAP TAIRSLMSYG KEPLAGIDLS
SLRVLGSVGE PINEEAWHWF DEEVGHKNCP IVDTWWQTET GGLMISPIAF VTPLKPACAT
LPLPGIQPIL VDEQGKEIEG NGVNGNLCIK FPWPGMLRTT YGDHERCKQT YFSTYPDLYF
TGDGCMRDED GYYKITGRVD DVINVSGHRI GTAEVENAIN MHAGVVESAV VGYPHEIKGQ
GIFAFVIYPK LHSESELTKK DILQTVTRVI GAIAKPDKIL FVTGLPKTRS GKIMRRILRK
IAEGDTENLG DTSTLLDPAV VDEIIAAAKK L
//
