ID   A0A1H4E4K3_9BACT        Unreviewed;       759 AA.
AC   A0A1H4E4K3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=SAMN05660909_03475 {ECO:0000313|EMBL:SEA79490.1};
OS   Chitinophaga terrae (ex Kim and Jung 2007).
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=408074 {ECO:0000313|EMBL:SEA79490.1, ECO:0000313|Proteomes:UP000199656};
RN   [1] {ECO:0000313|Proteomes:UP000199656}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23920 {ECO:0000313|Proteomes:UP000199656};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; FNRL01000016; SEA79490.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4E4K3; -.
DR   STRING; 408074.SAMN05660909_03475; -.
DR   Proteomes; UP000199656; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF13290; CHB_HEX_C_1; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..759
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011490704"
FT   DOMAIN          31..152
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          156..500
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   DOMAIN          644..734
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|Pfam:PF00754"
FT   ACT_SITE        331
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   759 AA;  85191 MW;  9166980BC6B8D6D6 CRC64;
     MKSISYLCMI LIGLCCACAT TNEEIPKGHF NVIPLPANIQ ANSDSFLLDK HTVIVASEPA
     DITTASLLNT WIKELTGYEL EVKKEAGDNA ITLHSGSDST QPEGYTLKVG NHQITIQGNT
     SSGTFYGVQT LIQLIPVAKA KAMYIPGGEI TDSPRFAYRG LHLDVGRHFF PVAFIKKYID
     LMAMHKFNTF HWHLTEDQGW RIEIRKYPRL QEIASKRKET MKGRYADNQF DGKPYGGYYT
     QEEVREVVKY AQDHFVTVIP EIEMPGHSLA ALAAYPNLGC TGGPYETGTR WGVYDDVYCA
     GNDSVFLFLQ DVLDEVMTLF PSKYIHIGGD ECPKVRWEKC PKCQARMKQE GLKNEHALQS
     YFIQRIEKYL NSKGRQIIGW DEILEGGLAP NATVMSWRGI EGGIAAAKQH HDVIMTPGDY
     CYFDHYQSRS ANEPLAIGGY LPVKKVYEYE PVPAALTQEE GKYIKGAQAN LWTEYIANSD
     YLEYMAYPRA AALAEVLWTP ASRKNYDDFV NRLKEHVARL DKKKVNYAKH VFEVTGKITV
     KDGKESLTLD SKLNGGKIFF TTDSTAPTPQ STPYTQPVAI EKTMTIRAQV FQDNKPFGNE
     YNQRFVYSKA LGRQVKLGAE ADQAYRPSAE VLVNGIRGSE SYNDNEWFGY KNSDFEAVVD
     LDSVQPISSI GIGVLVNKND WIYPPKQVSF SVSEDGKNYK TIFQQTTFSQ QGINNVRSVF
     ATVNARFVKV TVQRFGKIPA GAEGAGDQAW LMVDELEVQ
//