ID   A0A1H4FFQ1_9GAMM        Unreviewed;       943 AA.
AC   A0A1H4FFQ1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain {ECO:0000313|EMBL:SEA96179.1};
GN   ORFNames=SAMN05660964_02960 {ECO:0000313|EMBL:SEA96179.1};
OS   Thiothrix caldifontis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Thiotrichaceae; Thiothrix.
OX   NCBI_TaxID=525918 {ECO:0000313|EMBL:SEA96179.1, ECO:0000313|Proteomes:UP000199397};
RN   [1] {ECO:0000313|EMBL:SEA96179.1, ECO:0000313|Proteomes:UP000199397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21228 {ECO:0000313|EMBL:SEA96179.1,
RC   ECO:0000313|Proteomes:UP000199397};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNQP01000020; SEA96179.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4FFQ1; -.
DR   STRING; 525918.SAMN05660964_02960; -.
DR   OrthoDB; 9768004at2; -.
DR   Proteomes; UP000199397; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.90.1580.10; paralog of FGE (formylglycine-generating enzyme); 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR049052; nSTAND1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005532; SUMF_dom.
DR   InterPro; IPR042095; SUMF_sf.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR23150:SF35; BLL6746 PROTEIN; 1.
DR   PANTHER; PTHR23150; SULFATASE MODIFYING FACTOR 1, 2; 1.
DR   Pfam; PF03781; FGE-sulfatase; 1.
DR   Pfam; PF20703; nSTAND1; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199397}.
FT   DOMAIN          6..142
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   943 AA;  107540 MW;  B94B0BD2D478AE6B CRC64;
     MADAPQTAQI FLSYSRTNLE AAIVLRTELE KAGFTVFRDE DSIRAGDNWM ERLQAALQGC
     SAFVLLYGRE GVRRWVWAEV QYALSRNLSP HDDALRLPIF PVLLPEGDLH NLPPFLSLFQ
     IQRWQPEQAL PATLIQAIRD KTELLDDSNT FEGCPYLGLS AFQPEHANLF FGRREETLDA
     LKLLGTLRDD VRPDRIRVDG QYCRWLQIEG NSGSGKSSLV NAGMLPLIQQ GILWARTGYE
     HWHILKPMMP GEKPLQQLAE VLEHSLLPEQ QRDIGKRHQC LLADEKALAL RLRDFKQDGK
     AFLLVVDQFE ELFTFSDQTE KLHFDMQLYT ALQDKDCPLF VISTVRIDFL EHFEQLLCLK
     ALYRQRLCER YLLPTVTQRG LQEAIEQPAR LAGLDVSAVT TAMLNDAKNE PGALPLVENA
     LRVLWEQREG NRLSGELYLS KGGIAGLLEE QADDLLKRLD SDLPKGKADA LELLLALTRI
     NDEGRHTRRR LPLGEARLAA GGKQADPKRG QQVIDYLTGR LTPDGGNRKA NGSLRLLVTV
     GDNEHDQSID LIHETLIRAK GKDEVTGKQV GYWKTLYDYI DKNRERGFYR DQLARQAKEW
     QGKKGLGRWF NLAGWGDLRA YRKLRPERGS VDERFLSRSR RVGWLQGGAL VLLLGFVGES
     YLWTLNNGLP PNYMLTQQKF RLMDWGILPE PLPEMLEIPL SVGEFQMGDS NEDKYKNSMK
     NPISKESVNL GDPPIRVTLT NPFALGKFEL TYEQYDYYVW SQRENDDSPA YPSNAPNENA
     RGQRAVVNVS WNDAQNYLQW LSIRTGDNYR LPTEAEWEYA ARGGLTTPYW WGNNIGKNNA
     NCRNCGSQWD NTFVAPVGSF KPNPFGLYDT VGNVWEWTCS DWRMIFNGDE KICTQFESDF
     RVSRGGSWNI DAIYVNAASR SKDNVVERHN NVGLRVLRTA RTH
//