ID   A0A1H4HJ62_9BURK        Unreviewed;       678 AA.
AC   A0A1H4HJ62;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Transcriptional regulator, propionate catabolism operon regulatory protein {ECO:0000313|EMBL:SEB21715.1};
GN   ORFNames=SAMN05192564_109170 {ECO:0000313|EMBL:SEB21715.1};
OS   Paraburkholderia sartisoli.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=83784 {ECO:0000313|EMBL:SEB21715.1, ECO:0000313|Proteomes:UP000198638};
RN   [1] {ECO:0000313|EMBL:SEB21715.1, ECO:0000313|Proteomes:UP000198638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 24000 {ECO:0000313|EMBL:SEB21715.1,
RC   ECO:0000313|Proteomes:UP000198638};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNRQ01000009; SEB21715.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4HJ62; -.
DR   STRING; 83784.SAMN05192564_109170; -.
DR   Proteomes; UP000198638; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR012704; Sig_transdc_resp-reg_PrpR.
DR   InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   NCBIfam; TIGR02329; propionate_PrpR; 1.
DR   PANTHER; PTHR32071:SF21; PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN; 1.
DR   PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF06506; PrpR_N; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198638};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          221..269
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          346..585
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000259|PROSITE:PS50045"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   678 AA;  74069 MW;  A294FB89A10C3F84 CRC64;
     MSESSVHNRH DEFLRPQPRT IMTPLPVSGP RPRVWAIGIS KLRDLYRDIA GEYDARADLR
     LISRGFEDAV NEIAAAGADR PDIVVAAGSN GTYLKARVSV PVVLVAPTGF DVMHALARAR
     RDGASVALVT HGETPGELRR FVSAYGIDVV FASYESAQDA ETCVLDLRDR GVETVVGPGL
     VTDLAVRAGM GAVFLYSRAS VRTAFDNALD VAQATRREAV RRQRLDSVLQ HLRDGVVALD
     AQGRVEAINQ RLALTLGIDP ATAAGKLLLD LAPDIANAVP DAEGESLETV RGVSYVVHRG
     PLADNGVTTG TVLTFQESRA VERLDRTLRS RQRAQQFAAR YTLDDIVGEC AAIERVRSLV
     RRYAQSDATV LIRGESGTGK EMVAQSIHQA SARRDFPFVA INCGSFPEAL LESELFGYEE
     GAFTGARRGG KAGLIEAAHR GTLFLDEIGE MPLPLQSRLL RVLQEREVVR LGSTEPTRID
     VRIVAATHRG LTEGIDAGEF RADLYYRLNI LNIALPPLRE RQADILPLAA ELLVQAARRE
     PRLARQVRNG TDAANALHAV RVPLSEHSWP GNVRELQNVI ERIAVELADP EAGELTHDVL
     RSIAPELFER TAREAASLTL RQRSRRVEAD EIRAALDACN GDRDQVCEML GISKTTLWRK
     LNDVAQAGGA KPRSRSLR
//