ID   A0A1H4MNR8_9BACL        Unreviewed;       339 AA.
AC   A0A1H4MNR8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SEB84639.1};
GN   ORFNames=SAMN05443246_2109 {ECO:0000313|EMBL:SEB84639.1};
OS   Paenibacillus sp. GP183.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1882751 {ECO:0000313|EMBL:SEB84639.1, ECO:0000313|Proteomes:UP000199177};
RN   [1] {ECO:0000313|EMBL:SEB84639.1, ECO:0000313|Proteomes:UP000199177}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GP183 {ECO:0000313|EMBL:SEB84639.1,
RC   ECO:0000313|Proteomes:UP000199177};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNSW01000001; SEB84639.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4MNR8; -.
DR   STRING; 1882751.SAMN05443246_2109; -.
DR   OrthoDB; 9805416at2; -.
DR   Proteomes; UP000199177; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR   CDD; cd05300; 2-Hacid_dh_1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199177}.
FT   DOMAIN          132..306
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   339 AA;  37804 MW;  410FD8B4B763A612 CRC64;
     MSFTVLIASY LEPEQVERIR QTLPGLRVLY DPELLYKPRY QADHIGPSDW SRTPEQEKKF
     LSWLAEADIM WDFDRRLTPR LTELAPRLKW IQATSSGIGD IVKKFGLDQS SITITNAAGI
     HAIPLAEHSL LSMLYFTKNV PFIRKEQAAH HWERYCSKEL RGSTLGVVGL GAVGREVARL
     AKANGLKVLG VKRNVDMDPA SLNVDELYPQ SSLSMVLPRC DFLVLICPHT PETEGMIGER
     ELALLPKGAV LINIARGAVV DEDALIASLQ SGHLAGAALD VARTEPLPAD SPLWSMENVL
     ITPHSASTVT QENQRLTDLF CENLQRFSEE RQLLNLFKA
//