ID   A0A1H4MRK3_9ACTN        Unreviewed;       360 AA.
AC   A0A1H4MRK3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=dTDP-L-rhamnose 4-epimerase {ECO:0000313|EMBL:SEB85619.1};
GN   ORFNames=SAMN04489844_1200 {ECO:0000313|EMBL:SEB85619.1};
OS   Nocardioides exalbidus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=402596 {ECO:0000313|EMBL:SEB85619.1, ECO:0000313|Proteomes:UP000198742};
RN   [1] {ECO:0000313|Proteomes:UP000198742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22017 {ECO:0000313|Proteomes:UP000198742};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000256|ARBA:ARBA00007637}.
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DR   EMBL; FNRT01000002; SEB85619.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4MRK3; -.
DR   STRING; 402596.SAMN04489844_1200; -.
DR   OrthoDB; 9801785at2; -.
DR   Proteomes; UP000198742; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          11..287
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   360 AA;  38583 MW;  66EBEC4262F835BF CRC64;
     MSSSQQAGGR VLVTGGAGFI GTTLARELAD SAEQWVVLDN LHPQVHPGSE PPADLPGSVD
     LRVGDVTSAD DLDAVVAELR PDTVVHLAAE TGTAQSLSES TRHGMVNVVG TTQLLDSLTR
     AGHVPSHFVL TSSRAVYGEG VWRNVDGSTF QPGLRTHAQL ESGKWDHGDG AAHVPNTVLG
     THPNPINVYG ATKLAQEQIL SAWTGSHDTR LSVLRLQNVY GPRQSLSNPY TGIVSLFSRL
     AREGQSIPLY EDGEITRDFV HIDDVVSALV AAIAHKPADH MRTVDVGSGI RTTIGDLARE
     VARYHSAPEP HVTGQYRDGD VRHASCDVEV TLRQLDWRPE VGLREGVAGL QEWIAGELGR
//