ID A0A1H4MW43_9BACL Unreviewed; 746 AA.
AC A0A1H4MW43;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:SEB86974.1};
GN ORFNames=SAMN05443246_2186 {ECO:0000313|EMBL:SEB86974.1};
OS Paenibacillus sp. GP183.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1882751 {ECO:0000313|EMBL:SEB86974.1, ECO:0000313|Proteomes:UP000199177};
RN [1] {ECO:0000313|EMBL:SEB86974.1, ECO:0000313|Proteomes:UP000199177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GP183 {ECO:0000313|EMBL:SEB86974.1,
RC ECO:0000313|Proteomes:UP000199177};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; FNSW01000001; SEB86974.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4MW43; -.
DR STRING; 1882751.SAMN05443246_2186; -.
DR Proteomes; UP000199177; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199177}.
FT DOMAIN 184..262
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 746 AA; 84530 MW; 34EE0CF7478A081A CRC64;
MGGWYLQPDC NMPSGESFVR QMLLGRNYFQ EKFGVKSTTA INFDPFGHTR GLVQIMSKAG
FDSYIFCRPT QKDCELPAND FVWVGYDGSE IIGHRADEFY NSPRGKADEK VREWIDKTVD
QPIGSVLWGV GNHGGGPSRE DLEKLKLLMA ETKDVQIIHS TPEAFFKELR IVRSSLPRHE
KDVNAWAPGC YTSQIRIKQK HRLLENEIYM LEKMMSHSSL QGLTVYPYEL IHEAICDLMV
TEFHDVLPGS SIQPVEEASL RLVDHGLEII SRLKARAFFA LASGQKKAEE GEIPILIYNP
HPYKVRGAFE CEFQLADQNW KDEFSMPVVY KDGVRIASQA EKELSNLNLD WRKRVVFQAE
LEPGQMNRFD VRLEMLPNKP APALQPQDGK ISFLTEELEV IINCKTGLID RYRANGVDYL
QSNAFVPIVI DDNDDPWGME GLSFRNVEGA FKLMSAEEGT RFSGIRGSRL ESVRMIEDGA
VRTVVEALFE YGDSFIIQTY KLPKKGTEIE VQIRAHWNEK SKMLKLSIPT LLVEGRYWGQ
VAYGRNELPG NGNEAVSQKW LAVIDEKQDL ALTCINDGVY GSDYNDGEVR ISLLRSAGYS
GHPIGDRPIM AQDRYSSRID QGERLYRFWF NAGKTSERME FIDREALSLN EKPFVLSFFP
SGSGALPENA LTLSDSTVLL TAFKRAELSN DYIIRLFEPT GTARETTLTI PALGIKQEIK
LGKFEIKTLR LDVAAKKIKE ASLMEE
//
