ID A0A1H4PWG6_9ACTN Unreviewed; 750 AA.
AC A0A1H4PWG6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Anaerobic selenocysteine-containing dehydrogenase {ECO:0000313|EMBL:SEC11650.1};
GN ORFNames=SAMN05216482_2163 {ECO:0000313|EMBL:SEC11650.1};
OS Streptomyces sp. PAN_FS17.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1855351 {ECO:0000313|EMBL:SEC11650.1, ECO:0000313|Proteomes:UP000199275};
RN [1] {ECO:0000313|Proteomes:UP000199275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAN_FS17 {ECO:0000313|Proteomes:UP000199275};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FNTN01000001; SEC11650.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4PWG6; -.
DR STRING; 1855351.SAMN05216482_2163; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000199275; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02762; MopB_1; 1.
DR CDD; cd02782; MopB_CT_1; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199275}.
FT DOMAIN 2..58
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 750 AA; 79139 MW; C251E7A8E000D7F4 CRC64;
MSRTALRICP LCEATCGLTL TIEGTAVTGA RGDRDDVFSR GFICPKGASF GAVDGDPDRL
RTPLVRRDGE LCEATWEEAF DAVAAGLRPV VERYGPNSVG VVLGNPNVHT VAGALYPPIL
MAGLRTRSVF TASTVDQMPK HVSSGLLYGD ALAIPVPDLD HTDHLLLIGA NPLESNGSLC
TAPDFPGKLK ALKARGGTLT VIDPRRTRTA RLADRHVAIR PGTDALLLAA MAYVLFEEDL
VALGELAPHV QGVEELRAEV RDFTPESVAD ACDVDAGTIR ALAHELAAAP TAAVYGRIGS
CTVPHGTLAS WLVDVLNVLT GNLDRPGGAL FPQAATDKTP RPAGPGHGFA LGRWHSRVSR
HPEAKGELPL SALAEEIDTA TAEGEAIRAL VAVASNPVLS APDGDRLDKA LGSLDFMVSV
DPYLNETSRH AHVVLPPPPP SQSPHHDFAF NTLAVRNQVR YTRAAVPLEP GRMAESEILA
RLILAATGMH GADPAAVDVM VVEQTLGKAV EEPHSPVHGR DPKELAAQLT GVSGPERRLD
MMLRLGPYGD GFGVRPDGLT LEKLLAHPHG IDLGPLKSRL PQPLKTVSGK VELLPAPIAG
DLPRLREALR HRPDGLVLVG RRHLRSNNSW MHNVPALTGG SNRCTLHIHP QDAERLGVRD
GAAVRLKGAG GEVTAPAEVT DAVRPGVVSL PHGWGHDRPG TRLGHAATDP GVNVNQLLDG
SLLDPLSGNA VLNGVPIEVS PVSEKITALT
//
