ID A0A1H4QY38_9PSEU Unreviewed; 638 AA.
AC A0A1H4QY38;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Succinate dehydrogenase / fumarate reductase flavoprotein subunit {ECO:0000313|EMBL:SEC24477.1};
GN ORFNames=SAMN04489727_3078 {ECO:0000313|EMBL:SEC24477.1};
OS Amycolatopsis tolypomycina.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=208445 {ECO:0000313|EMBL:SEC24477.1, ECO:0000313|Proteomes:UP000199622};
RN [1] {ECO:0000313|EMBL:SEC24477.1, ECO:0000313|Proteomes:UP000199622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44544 {ECO:0000313|EMBL:SEC24477.1,
RC ECO:0000313|Proteomes:UP000199622};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNSO01000004; SEC24477.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H4QY38; -.
DR STRING; 208445.SAMN04489727_3078; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000199622; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF89; SUCCINATE DEHYDROGENASE [IRON-SULFUR SUBUNIT] (SUCCINIC DEHYDROGENASE)-RELATED; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 10..429
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 487..604
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT COILED 500..527
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 322
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 638 AA; 70016 MW; 8AC60658F29F92E6 CRC64;
MTEVERHTYD VVVIGAGGAG LRAVIEARER GFRVAVVCKS LFGKAHTVMA EGGCAASMGN
ANSNDNWQVH FRDTMRGGKF LNNWRMAELH AKEAPDRVWE LETYGALFDR TADGRISQRN
FGGHTYPRLA HVGDRTGLEL IRTMQQKIVS LQQEDFAETG DYEAKIKVFA ECTVTELLTT
EGRIAGAFGY WRESGRFVLF EAPAVVLATG GIGKSFKVTS NSWEYTGDGH ALALRAGAKL
INMEFVQFHP TGMVWPPSVK GILVTEGVRG DGGVLKNSDG KRFMFEYVPD VFKGQYAESE
EEADRWYTDQ EKNRRTPDLL PRDEVARAIN SEVKEGRGSP HGGVFLDIAS RLPAEEIRKR
LPSMYHQFKE LADVDITAEP MEVGPTCHYV MGGIEVDPDT AAASVPGLFA AGECSGGMHG
SNRLGGNSLS DLLVFGRRAG LGAAEYVSGL DGRPAVQESD VDAAAKMALA PFDPPAGASA
ENPYTLHTEL QQSMNDLVGI IRKAEEMAQA LAKLDELRER ILRVTVEGHR QFNPGWHLAI
DLRNMLMVSE CVAKAALTRT ESRGGHTRDD YPGMEADWRN KLLVCSATAG DNPVVPDIDV
EVKEQVPLRQ DLLELFEFGE LGKYYTDSEL ETHPGSKA
//
