ID   A0A1H4RMT4_9BACL        Unreviewed;       842 AA.
AC   A0A1H4RMT4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Serine protease, subtilisin family {ECO:0000313|EMBL:SEC33215.1};
GN   ORFNames=SAMN05443246_3738 {ECO:0000313|EMBL:SEC33215.1};
OS   Paenibacillus sp. GP183.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1882751 {ECO:0000313|EMBL:SEC33215.1, ECO:0000313|Proteomes:UP000199177};
RN   [1] {ECO:0000313|EMBL:SEC33215.1, ECO:0000313|Proteomes:UP000199177}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GP183 {ECO:0000313|EMBL:SEC33215.1,
RC   ECO:0000313|Proteomes:UP000199177};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC       ECO:0000256|RuleBase:RU003355}.
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DR   EMBL; FNSW01000001; SEC33215.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4RMT4; -.
DR   STRING; 1882751.SAMN05443246_3738; -.
DR   OrthoDB; 9798386at2; -.
DR   Proteomes; UP000199177; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07484; Peptidases_S8_Thermitase_like; 1.
DR   Gene3D; 2.60.120.380; -; 3.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR001119; SLH_dom.
DR   InterPro; IPR034084; Thermitase-like_dom.
DR   PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR   PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF00395; SLH; 3.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF89260; Collagen-binding domain; 2.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51272; SLH; 3.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00136; SUBTILASE_ASP; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000199177};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          667..730
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   DOMAIN          731..786
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   DOMAIN          787..842
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   ACT_SITE        69
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        102
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        254
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   842 AA;  92717 MW;  2D1B59FE2DD44CCE CRC64;
     MNRFYQLILL ICIILAVEGA GITVQVQAAP SLSTDPMRVK QTYLDLIHID AAWAAAGVNS
     SSVIVAVVDT GVDLTHPDLE GKLVDGINLI NPGTKPLDDN GHGTNVAGII AASLNNDKGI
     AGIAPNAKIM PIKALESDGT GGELKLGQGV RYAVDHGAQI VVLSLGLNKS SNELSAAIQY
     AEDHHVLLVA ASGNEGTSIK YPAAYPTVLA VGGVTADKHA DYRSNFGPEL DLVAPWDVFT
     TKLGGGYEYK DGTSMSAPQV AGVAALLLGK YPQMTPLQVR EQLLQSAEDL ETPGWDATTG
     YGLLRADLAL TKPFNPDRFE PNNSKQQASS IPVQAIIHSS LSSGQDQDWF VMDCPYDGTV
     KVTIRSADGT VILLRAESAL TGSGITYSAG TAPTSIEVKK GRTYLQLQTA DRQRLTSLNY
     SLQTEFQIYR DQFENNDKQY QAFTLPARTQ TIRGTFHQKG DVDWFMLPLA TSGTLRIRCS
     VDTGRIDPVI LFQKKGEKSM TIDQAGDGAT EITPEMELLP GDYYIRISNA KDFSEPITGE
     YTLSIEYTPK LLDPNEPNDK PYQATFAGLF TDYPGLFHSN QDEDWFEVRL SNEGLTQLSV
     TNIPLDRTLY GTLYDNSLNE KFSFQNLTGN SSLFVEQKLP AGTYYIKLRA NESFLDQMYH
     FKAGVYLLNS GYIDISGHWA ADPISNLTRK ELISGYGNYR FAPDRPITRA EASAMLVKAF
     QLTKLRDIQY TDLNPEHWAY SYIAKTEQAG LVEGYPDQSF QPDRTLTRME MTQMLAKRLN
     MAGKRRGDSP FTDVSNEYWG VGILKQMWAD GWISGYPDVT FRPEEQATRA EFAMLLDRIL
     NR
//