ID   A0A1H4TD47_9MICO        Unreviewed;       302 AA.
AC   A0A1H4TD47;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cobalt-zinc-cadmium efflux system protein {ECO:0000313|EMBL:SEC54071.1};
GN   ORFNames=SAMN04489806_3167 {ECO:0000313|EMBL:SEC54071.1};
OS   Microbacterium humi.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=640635 {ECO:0000313|EMBL:SEC54071.1, ECO:0000313|Proteomes:UP000199183};
RN   [1] {ECO:0000313|EMBL:SEC54071.1, ECO:0000313|Proteomes:UP000199183}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21799 {ECO:0000313|EMBL:SEC54071.1,
RC   ECO:0000313|Proteomes:UP000199183};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FNRY01000002; SEC54071.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H4TD47; -.
DR   STRING; 640635.SAMN04489806_3167; -.
DR   OrthoDB; 9809646at2; -.
DR   Proteomes; UP000199183; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR036837; Cation_efflux_CTD_sf.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   NCBIfam; TIGR01297; CDF; 1.
DR   PANTHER; PTHR11562; CATION EFFLUX PROTEIN/ ZINC TRANSPORTER; 1.
DR   PANTHER; PTHR11562:SF17; LD05335P; 1.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR   SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199183};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        17..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   302 AA;  31776 MW;  F868B17593C956F3 CRC64;
     MAHDHASTTT NRAKLRIVVV IVAAMLVAEV VGGILTGSLS LLADAGHMFS DLTGLLIALV
     AISIAARPAT DRHTWGFQRT EVLAALLNGL ILAAVAVSVA IEGVRRLVRP EPVDVEGGWM
     LVVAIAGLVA NAASLMILRD SAQQSINIKG AYLEVFGDLF GSAVVAAAAI VILLTGFAPA
     DAIASLVIAA GILPRAVILL RDVWRVLNES TPVGIDVEML REHLRSADGV VDVHDVHVWL
     ITSGEPVFTA HVIADAAVFR EGRTGELLDT LGACLSGHFD VAHSTFQLEP EQHAGHEDKH
     HA
//